Hydrogen Sulfide: Emerging Role in Bladder, Kidney, and Prostate Malignancies
المؤلفون المشاركون
Akbari, Masoud
Sogutdelen, Emrullah
Juriasingani, Smriti
Sener, Alp
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-11-03
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Hydrogen sulfide (H2S) is the latest member of the gasotransmitter family and known to play essential roles in cancer pathophysiology.
H2S is produced endogenously and can be administered exogenously.
Recent studies showed that H2S in cancers has both pro- and antitumor roles.
Understanding the difference in the expression and localization of tissue-specific H2S-producing enzymes in healthy and cancer tissues allows us to develop tools for cancer diagnosis and treatment.
Urological malignancies are some of the most common cancers in both men and women, and their early detection is vital since advanced cancers are recurrent, metastatic, and often resistant to treatment.
This review summarizes the roles of H2S in cancer and looks at current studies investigating H2S activity and expression of H2S-producing enzymes in urinary cancers.
We specifically focused on urothelial carcinoma, renal cell carcinoma, and prostate cancer, as they form the majority of newly diagnosed urinary cancers.
Recent studies show that besides the physiological activity of H2S in cancer cells, there are patterns between the development and prognosis of urinary cancers and the expression of H2S-producing enzymes and indirectly the H2S levels.
Though controversial and not completely understood, studying the expression of H2S-producing enzymes in cancer tissue may represent an avenue for novel diagnostic and therapeutic strategies for addressing urological malignancies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Akbari, Masoud& Sogutdelen, Emrullah& Juriasingani, Smriti& Sener, Alp. 2019. Hydrogen Sulfide: Emerging Role in Bladder, Kidney, and Prostate Malignancies. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1202633
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Akbari, Masoud…[et al.]. Hydrogen Sulfide: Emerging Role in Bladder, Kidney, and Prostate Malignancies. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1202633
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Akbari, Masoud& Sogutdelen, Emrullah& Juriasingani, Smriti& Sener, Alp. Hydrogen Sulfide: Emerging Role in Bladder, Kidney, and Prostate Malignancies. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1202633
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1202633
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر