Spontaneous Slowing and Regressing of Tumor Growth in ChildhoodAdolescent Papillary Thyroid Carcinomas Suggested by the Postoperative Thyroglobulin-Doubling Time
المؤلفون المشاركون
Kasahara, Toshihiko
Kudo, Takumi
Ito, Mitsuru
Nishihara, Eijun
Miyauchi, Akira
Kihara, Minoru
Ito, Yasuhiro
Miya, Akihiro
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-16
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Children and adolescents with papillary thyroid carcinomas (PTCs) have generally excellent prognoses despite their frequent extended disease.
The tumor growth of young patients’ PTCs might show spontaneous slowing postoperatively.
We compared young PTC patients’ postoperative thyroglobulin-doubling time (Tg-DT) with their preoperative hypothetical tumor volume-doubling time (hTV-DT).
Methods.
Fourteen PTC patients aged ≤18 years who underwent total thyroidectomy at Kuma Hospital in 1998–2016 had biochemically persistent disease postoperatively.
We calculated their Tg-DTs and estimated their preoperative TV-DTs with the tumor size and the patient’s age at surgery, presuming that a single cancer cell was present at the patient’s birth.
Results.
Twelve patients had positive Tg-DTs ranging from 2.0 to 147 years, and the remaining two had negative Tg-DTs, indicating slow growth or even regression.
The hTV-DTs were 0.3–0.6 years (median 0.5 years), which were significantly shorter than the Tg-DTs (p<0.001), indicating much faster growth preoperatively.
The analyses of the nine patients without radioactive iodine administration (RAI) gave similar results (p<0.01).
Conclusions.
Irrespective of RAI, the patients’ postoperative Tg-DTs were significantly longer than their preoperative hTV-DTs and were negative values in two patients, indicating that the growth of these young patients’ PTCs had spontaneously slowed or even regressed postoperatively.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kasahara, Toshihiko& Miyauchi, Akira& Kudo, Takumi& Nishihara, Eijun& Ito, Mitsuru& Ito, Yasuhiro…[et al.]. 2018. Spontaneous Slowing and Regressing of Tumor Growth in ChildhoodAdolescent Papillary Thyroid Carcinomas Suggested by the Postoperative Thyroglobulin-Doubling Time. Journal of Thyroid Research،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1203089
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kasahara, Toshihiko…[et al.]. Spontaneous Slowing and Regressing of Tumor Growth in ChildhoodAdolescent Papillary Thyroid Carcinomas Suggested by the Postoperative Thyroglobulin-Doubling Time. Journal of Thyroid Research No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1203089
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kasahara, Toshihiko& Miyauchi, Akira& Kudo, Takumi& Nishihara, Eijun& Ito, Mitsuru& Ito, Yasuhiro…[et al.]. Spontaneous Slowing and Regressing of Tumor Growth in ChildhoodAdolescent Papillary Thyroid Carcinomas Suggested by the Postoperative Thyroglobulin-Doubling Time. Journal of Thyroid Research. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1203089
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203089
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر