Metabolic Syndrome and Subclinical Hypothyroidism: A Type 2 Diabetes-Dependent Association
المؤلفون المشاركون
Cabrera, Mayela
Cano, Climaco
Salazar, Juan
Rojas, Milagros
Estrella, Viviana
Ordoñez, María
Hernández, Juan Diego
Arias, Víctor
Rojas, Joselyn
Bermúdez, Valmore
Áñez, Roberto
Chacín, Maricarmen
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Introduction.
Subclinical hypothyroidism (ScH) is an endocrine alteration that is related to cardiovascular risk factors, including those categorized as components of the Metabolic Syndrome (MS).
However, findings in prior reports regarding an association between these alterations are inconsistent.
The purpose of this study was to determine the relationship between both entities in adult subjects from Maracaibo City, Venezuela.
Materials and Methods.
The Maracaibo City Metabolic Syndrome Prevalence Study is a descriptive, cross-sectional study with random and multistage sampling.
In this substudy, 391 individuals of both genders were selected and TSH, free T3, and free T4 tests were performed as well as a complete lipid profile, fasting glycaemia, and insulin blood values.
ScH was defined according to the National Health and Nutrition Examination Survey (NHANES) criteria: high TSH (≥4.12mUI/L) and normal free T4 (0.9-1,9 ng/dL) in subjects without personal history of thyroid disease.
MS components were defined according to IDF/AHA/NHLBI/WHF/IAS/IASO-2009 criteria.
A multiple logistic regression analysis was used to assess the relationship between MS components and ScH diagnosis.
Results.
Of the evaluated population, 10.5% (n=41) was diagnosed with ScH, with a higher prevalence in women (female: 13.6% versus male: 7.7%; χ2=3.56, p=0.05).
Likewise, 56.1% (n=23) of the subjects with ScH were diagnosed with MS (χ2=4.85; p=0.03), being hyperglycemia the main associated criterion (χ2=11.7; p=0.001).
In multivariable analysis, it was observed that the relationship was exclusive with the presence of type 2 diabetes mellitus (T2DM) OR: 3.22 (1.14-9.14); p=0.03.
Conclusion.
The relationship between ScH and MS in our population is dependent on the presence of hyperglycemia, specifically T2DM diagnosis, findings that vary from those previously reported in Latin American subjects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bermúdez, Valmore& Salazar, Juan& Áñez, Roberto& Rojas, Milagros& Estrella, Viviana& Ordoñez, María…[et al.]. 2018. Metabolic Syndrome and Subclinical Hypothyroidism: A Type 2 Diabetes-Dependent Association. Journal of Thyroid Research،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1203094
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bermúdez, Valmore…[et al.]. Metabolic Syndrome and Subclinical Hypothyroidism: A Type 2 Diabetes-Dependent Association. Journal of Thyroid Research No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1203094
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bermúdez, Valmore& Salazar, Juan& Áñez, Roberto& Rojas, Milagros& Estrella, Viviana& Ordoñez, María…[et al.]. Metabolic Syndrome and Subclinical Hypothyroidism: A Type 2 Diabetes-Dependent Association. Journal of Thyroid Research. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1203094
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203094
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر