Temporal Changes on the Risks and Complications of Posttransplantion Diabetes Mellitus Following Cardiac Transplantation
المؤلفون المشاركون
Racine, Normand
Iannino, Nadia
Nasri, Amine
Räkel, Agnès
Ducharme, Anique
Lachance, Kim
Tremblay-Gravel, Maxime
Fortier, Annik
White, Michel
de Denus, Simon
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-08
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
Recent changes in the demographic of cardiac donors and recipients have modulated the rate and risk, associated with posttransplant diabetes mellitus (PTDM).
We investigated the secular trends of the risk of PTDM at 1 year and 3 years after transplantation over 30 years and explored its effect on major outcomes.
Methods.
Three hundred and three nondiabetic patients were followed for a minimum of 36 months, after a first cardiac transplantation performed between 1983 and 2011.
Based on the year of their transplantation, the patients were divided into 3 eras: (1983-1992 [era 1], 1993-2002 [era 2], and 2003-2011 [era 3]).
Results.
In eras 1, 2, and 3, the proportions of patients with PTDM at 1 versus 3 years were 23% versus 39%, 21% versus 26%, and 33% versus 38%, respectively.
Independent risk factors predicting PTDM at one year were recipient’s age, duration of cold ischemic time, treatment with furosemide, and tacrolimus.
There was a trend for overall survival being worse for patients with PTDM in comparison to patients without PTDM (p = 0.08).
Patients with PTDM exhibited a significantly higher rate of renal failure over a median follow-up of 10 years (p = 0.03).
Conclusion.
The development of PTDM following cardiac transplantation approaches 40% at 3 years and has not significantly changed over thirty years.
The presence of PTDM is weakly associated with an increased mortality and is significantly associated with a worsening in renal function long-term following cardiac transplantation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Iannino, Nadia& Nasri, Amine& Räkel, Agnès& Ducharme, Anique& Lachance, Kim& Racine, Normand…[et al.]. 2018. Temporal Changes on the Risks and Complications of Posttransplantion Diabetes Mellitus Following Cardiac Transplantation. Journal of Transplantation،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1203163
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Iannino, Nadia…[et al.]. Temporal Changes on the Risks and Complications of Posttransplantion Diabetes Mellitus Following Cardiac Transplantation. Journal of Transplantation No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1203163
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Iannino, Nadia& Nasri, Amine& Räkel, Agnès& Ducharme, Anique& Lachance, Kim& Racine, Normand…[et al.]. Temporal Changes on the Risks and Complications of Posttransplantion Diabetes Mellitus Following Cardiac Transplantation. Journal of Transplantation. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1203163
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203163
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر