![](/images/graphics-bg.png)
Metastatin as a Marker for Hyperandrogenemia in Iraqi Women with Polycystic Ovary Syndrome
المؤلفون المشاركون
Abdalqader, Manal Madany
Hussein, Shatha Sami
المصدر
Obstetrics and Gynecology International
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-25
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
Kisspeptin 1 might reflect increased androgen level in polycystic ovarian syndrome instead of other markers.
Study Design.
A case control study was performed in Al-Yarmouk Teaching Hospital from 1st of July 2016 to 1st of July 2017; it involved 87 women divided into two groups: 44 women diagnosed as PCOS, 22 women with BMI ≥ 25 kg/m2 and 22 women with BMI < 25 kg/m2, and another 43 women without PCOS, 22 women with BMI ≥ 25 kg/m2 and 21 women with BMI < 25 kg/m2.
Hormonal, metabolic profiles, and hirsutism scores, as well as serum kisspeptin level, were assessed by using Human Kisspeptin 1(KISS-1) ELISA Kit.
The blood samples between days 2 and 5 of menstrual cycle were drawn by an disposable sterile syringe and collected in EDTA containing tubes (as anticoagulant), and the hormonal profile was measured using a biotech ELISA reader.
Result.
Serum level of kisspeptin was significantly higher in PCOS compared to control (322.4 vs.
235.3 ng/L, respectively).
There was no significant difference in age, BMI, and parity between control and PCOS; the frequency of hirsutism, acne, elevated LH, and increased free testosterone (fTT) were significantly higher in PCOS compared to control.
Kisspeptin shows a direct significant correlation with hirsutism and fTT (r = 0.648, 0.238, respectively).
In ROC analysis, kisspeptin had AUC (95% CI) = 0.874 (0.785–0.935) for predicting PCOS.
Conclusion.
Kisspeptin levels might be used as a marker for hyperandrogenemia in polycystic ovarian syndrome.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abdalqader, Manal Madany& Hussein, Shatha Sami. 2020. Metastatin as a Marker for Hyperandrogenemia in Iraqi Women with Polycystic Ovary Syndrome. Obstetrics and Gynecology International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1203342
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abdalqader, Manal Madany& Hussein, Shatha Sami. Metastatin as a Marker for Hyperandrogenemia in Iraqi Women with Polycystic Ovary Syndrome. Obstetrics and Gynecology International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1203342
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abdalqader, Manal Madany& Hussein, Shatha Sami. Metastatin as a Marker for Hyperandrogenemia in Iraqi Women with Polycystic Ovary Syndrome. Obstetrics and Gynecology International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1203342
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203342
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)