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Renal Dysfunction Is an Independent Risk Factor for Poor Outcome in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis: A New Cutoff Value
المؤلفون المشاركون
Colak, Ertugrul
Uzuner, Nevzat
Baş, Demet Funda
Sadeghi-Hokmabadi, Elyar
Taheraghdam, Aliakbar
Hashemilar, Mazyar
Farhoudi, Mehdi
Savadi Oskouei, Daryoush
Yazdchi, Mohammad
Özdemir, Atilla Özcan
Mirnour, Reshad
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-01-03
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
This study was set to assess the effect of renal dysfunction on outcome of stroke patients treated with intravenous thrombolysis (IVT).
Methods.
This multicenter research involved 403 patients from January 2009 to March 2015.
Patients were divided into two groups: (1) control group with GFR ≥ 45 mL/min/1.73 m2 and (2) low GFR group with GFR < 45 mL/min/1.73 m2.
Outcome measurements were poor outcome (mRS 3–6) and mortality at 3 months and symptomatic intracerebral hemorrhage (SICH) within the first 24–36 hours.
Univariate and multivariate regression analyses were performed, and odds ratios (ORs) were determined at 95% confidence intervals (CIs).
Results.
Univariate analyses determined that every decrease of GFR by 10 mL/min/1.73 m2 significantly increased the risk of poor outcome (OR 1.19, 95% CI 1.09–1.30, p<0.001) and mortality (OR 1.18, 95% CI 1.06–1.32, p=0.002).
In multivariate regression, adjusted for all variables with p value < 0.1, low GFR (GFR < 45 versus GFR equal to or more than 45) was associated with poor outcome (OR adjusted 2.15, 95% CI 1.01–4.56, p=0.045).
Conclusion.
In IVT for acute stroke, renal dysfunction with GFR < 45 mL/min/1.73 m2 before treatment determined increased odds for poor outcome compared to GFR of more than 45 mL/min/1.73 m2.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sadeghi-Hokmabadi, Elyar& Baş, Demet Funda& Farhoudi, Mehdi& Taheraghdam, Aliakbar& Savadi Oskouei, Daryoush& Yazdchi, Mohammad…[et al.]. 2017. Renal Dysfunction Is an Independent Risk Factor for Poor Outcome in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis: A New Cutoff Value. Stroke Research and Treatment،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1203529
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sadeghi-Hokmabadi, Elyar…[et al.]. Renal Dysfunction Is an Independent Risk Factor for Poor Outcome in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis: A New Cutoff Value. Stroke Research and Treatment No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1203529
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sadeghi-Hokmabadi, Elyar& Baş, Demet Funda& Farhoudi, Mehdi& Taheraghdam, Aliakbar& Savadi Oskouei, Daryoush& Yazdchi, Mohammad…[et al.]. Renal Dysfunction Is an Independent Risk Factor for Poor Outcome in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis: A New Cutoff Value. Stroke Research and Treatment. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1203529
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203529
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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