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Increase of Vascular Endothelial Growth Factor and Decrease of MCP-1 and Some Updated Epidemiology Aspects of Cystic Echinococcosis Human Cases in Calabria Region
المؤلفون المشاركون
Focà, Alfredo
Galati, Luisa
Mazzitelli, Maria
Loria, Maria Teresa
Peronace, Cinzia
Catanzariti, Tatiana
Settembre, Pio
Dodaro, Gessica
Torti, Carlo
Giancotti, Aida
Liberto, Maria Carla
Barreca, Giorgio S.
Strazzulla, Alessio
Lamberti, Angelo G.
Quirino, Angela
Matera, Giovanni
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-14
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
We aim to investigate some of the pathogenetic mediators of the human echinococcosis and to obtain updated epidemiological findings on cases of echinococcosis in Calabria, Southern Italy.
Echinococcosis diagnosis was based on imaging, serological investigations, and molecular assay.
Indeed, real-time PCR indicated the presence of G2/G3 genotypes of Echinococcus granulosus complex.
Regarding pathogenesis, a relevant novel tool of immune depression should be deemed the reduced level of serum MCP-1.
Also, we found a previously unreported VEGF, possibly associated with neovascularization requested by the parasite cyst metabolism.
Cytokine profiles suggest a bias of the immunity toward Th2 and Treg responses.
Nitric oxide levels exhibited a significant decrease one week after therapy versus basal level measured before surgery and/or chemotherapy.
An increase of serum total IgE class and IgG4 subclass was found in Echinococcus-positive patients versus controls.
Our data demonstrated an endemic spreading, at least in the province of Catanzaro and neighboring Calabria territories, for such parasitosis with the novel issue of the number of female overcoming male cases.
In conclusion, the novel findings of this study were the increased VEGF and the reduced serum MCP-1 in the studied cases, as well as the number of Echinococcus-infected females overcoming the infected males.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Matera, Giovanni& Loria, Maria Teresa& Peronace, Cinzia& Catanzariti, Tatiana& Settembre, Pio& Giancotti, Aida…[et al.]. 2018. Increase of Vascular Endothelial Growth Factor and Decrease of MCP-1 and Some Updated Epidemiology Aspects of Cystic Echinococcosis Human Cases in Calabria Region. Mediators of Inflammation،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1203749
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Matera, Giovanni…[et al.]. Increase of Vascular Endothelial Growth Factor and Decrease of MCP-1 and Some Updated Epidemiology Aspects of Cystic Echinococcosis Human Cases in Calabria Region. Mediators of Inflammation No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1203749
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Matera, Giovanni& Loria, Maria Teresa& Peronace, Cinzia& Catanzariti, Tatiana& Settembre, Pio& Giancotti, Aida…[et al.]. Increase of Vascular Endothelial Growth Factor and Decrease of MCP-1 and Some Updated Epidemiology Aspects of Cystic Echinococcosis Human Cases in Calabria Region. Mediators of Inflammation. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1203749
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203749
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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