Unveiling the Role of Inflammation and Oxidative Stress on Age-Related Cardiovascular Diseases
المؤلفون المشاركون
Schini-Kerth, Valérie B.
Medeiros, Isac Almeida de
de Azevedo, Fátima de L. A. A.
da Silva, Tays A. F.
Almeida, Arthur José Pontes Oliveira de
de Almeida Rezende, Mathania Silva
Dantas, Sabine Helena
de Lima Silva, Sonaly
de Oliveira, Júlio César Pinheiro Lúcio
Alves, Rayanne Maira Felix Ribeiro
de Menezes, Geovânia Maria Sales
dos Santos, Pablo Ferreira
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-20، 20ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-05-09
دولة النشر
مصر
عدد الصفحات
20
التخصصات الرئيسية
الملخص EN
The global population above 60 years has been growing exponentially in the last decades, which is accompanied by an increase in the prevalence of age-related chronic diseases, highlighting cardiovascular diseases (CVDs), such as hypertension, atherosclerosis, and heart failure.
Aging is the main risk factor for these diseases.
Such susceptibility to disease is explained, at least in part, by the increase of oxidative stress, in which it damages cellular components such as proteins, DNA, and lipids.
In addition, the chronic inflammatory process in aging “inflammaging” also contributes to cell damage, creating a stressful environment which drives to the development of CVDs.
Taken together, it is possible to identify the molecular connection between oxidative stress and the inflammatory process, especially by the crosstalk between the transcription factors Nrf-2 and NF-κB which are mediated by redox signalling and are involved in aging.
Therapies that control this process are key targets in the prevention/combat of age-related CVDs.
In this review, we show the basics of inflammation and oxidative stress, including the crosstalk between them, and the implications on age-related CVDs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Almeida, Arthur José Pontes Oliveira de& de Almeida Rezende, Mathania Silva& Dantas, Sabine Helena& de Lima Silva, Sonaly& de Oliveira, Júlio César Pinheiro Lúcio& de Azevedo, Fátima de L. A. A.…[et al.]. 2020. Unveiling the Role of Inflammation and Oxidative Stress on Age-Related Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-20.
https://search.emarefa.net/detail/BIM-1203857
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Almeida, Arthur José Pontes Oliveira de…[et al.]. Unveiling the Role of Inflammation and Oxidative Stress on Age-Related Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-20.
https://search.emarefa.net/detail/BIM-1203857
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Almeida, Arthur José Pontes Oliveira de& de Almeida Rezende, Mathania Silva& Dantas, Sabine Helena& de Lima Silva, Sonaly& de Oliveira, Júlio César Pinheiro Lúcio& de Azevedo, Fátima de L. A. A.…[et al.]. Unveiling the Role of Inflammation and Oxidative Stress on Age-Related Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-20.
https://search.emarefa.net/detail/BIM-1203857
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203857
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر