Effects of Strong Acidic Electrolyzed Water in Wound Healing via Inflammatory and Oxidative Stress Response
المؤلفون المشاركون
Fadriquela, Ailyn
Sajo, Ma Easter Joy
Bajgai, Johny
Kim, Dong-Heui
Kim, Cheol-Su
Kim, Soo-Ki
Lee, Kyu-Jae
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-14
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Strong acidic electrolyzed water (StAEW) is known to inactivate microorganisms but is not fully explored in the medical field.
This study is aimed at exploring StAEW as a potential wound care agent and its mechanism.
StAEW (pH: 2.65, ORP: 1159 mV, ACC: 32.1 ppm) was sprayed three times a day to the cutaneous wounds of hairless mice for seven days.
Wound morphological and histological features and immune-redox markers were compared with saline- (Sal-) and alcohol- (Alc-) treated groups.
Results showed that the StAEW group showed a significantly higher wound healing percentage than the Sal group on days 2, 4, 5, and 6 and the Alc group on day 4.
The StAEW group also showed earlier mediation on proinflammatory cytokines such as tumor necrosis factor-α, interleukin- (IL-) 6, IL-1β, and keratinocyte chemoattractant.
In addition, basic fibroblast growth factor and platelet-derived growth factor were found to be significantly changed in favor of the fibroblast synthesis and angiogenesis.
In line, the StAEW group showed a controlled amount of ROS and significantly decreased compared to the Alc group.
The StAEW group also favored oxidative stress balance through antioxidant responses.
Additionally, matrix metalloproteinases (MMP) 9 and MMP1 were also modulated for keratinocyte and cell migration.
Taken together, this study has proven the wound healing effect of StAEW and its earlier mediation through oxidative and inflammatory responses.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fadriquela, Ailyn& Sajo, Ma Easter Joy& Bajgai, Johny& Kim, Dong-Heui& Kim, Cheol-Su& Kim, Soo-Ki…[et al.]. 2020. Effects of Strong Acidic Electrolyzed Water in Wound Healing via Inflammatory and Oxidative Stress Response. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1203956
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fadriquela, Ailyn…[et al.]. Effects of Strong Acidic Electrolyzed Water in Wound Healing via Inflammatory and Oxidative Stress Response. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1203956
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fadriquela, Ailyn& Sajo, Ma Easter Joy& Bajgai, Johny& Kim, Dong-Heui& Kim, Cheol-Su& Kim, Soo-Ki…[et al.]. Effects of Strong Acidic Electrolyzed Water in Wound Healing via Inflammatory and Oxidative Stress Response. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1203956
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203956
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر