Impairment on Cardiopulmonary Function after Marathon: Role of Exhaled Nitric Oxide
المؤلفون المشاركون
Cury-Boaventura, Maria Fernanda
Vieira, Rodolfo P.
Oliveira-Junior, Manoel Carneiro
Saraiva-Romanholo, Beatriz Mangueira
Sierra, Ana P. R.
Oliveira, Rodrigo A.
Pesquero, João B.
Benetti, Marino
Ghorayeb, Nabil
Kiss, Maria Augusta Peduti Dal Molin
Almeida, Francine Maria
Felix, Soraia Nogueira
Genaro, Isabella Santos
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-02-17
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
The endurance exercise is capable of inducing skeletal muscle, heart, and respiratory fatigue, evidenced by morphofunctional cardiac changes, release of myocardial injury biomarkers, and reduction of maximal voluntary ventilation and oxygen consumption (VO2) at peak exercise.
Purpose.
The aim of this study was to investigate whether marathoners present cardiac fatigue after marathon and whether it correlates with pulmonary levels of exhaled nitric oxide (eNO) and pulmonary inflammation.
Methods.
31 male marathoners, age 39±9 years, were evaluated by cardiopulmonary exercise test three weeks before and between three and 15 days after a marathon; eNO analysis and spirometry were evaluated before, immediately after, and 24 and 72 hours after the marathon, and sputum cellularity and cytokine level were assessed before and after the marathon.
Results.
Marathon induced an increase in the percentage of macrophages, neutrophils (from 0.65% to 4.28% and 6.79% to 14.11%, respectively), and epithelial cells and a decrease in cytokines in induced sputum, followed by an increase in eNO concentration (20±11 to 35±19 ppb), which presented a significant reduction 24 and 72 hours after marathon (9±12 e 12±9 ppb, p<0.05).
We observed a decrease in the spirometry parameters in all time points assessed after the marathon (p<0.05) as well as in cardiopulmonary capacity, evidenced by a reduction in VO2 and ventilation peaks (57±6 to 55±6 mL·min-1·Kg-1 and 134±19 to 132±18 Lpm, respectively, p<0.05).
Finally, we observed a negative correlation between the decrease in forced expiratory volume and decrease in eNO 24 and 72 hours after marathon (r=−0.4, p=0.05).
Conclusion.
Reduction in eNO bioavailability after marathon prevents the reduction in cardiopulmonary capacity induced by acute inflammatory pattern after marathon.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sierra, Ana P. R.& Oliveira-Junior, Manoel Carneiro& Almeida, Francine Maria& Benetti, Marino& Oliveira, Rodrigo A.& Felix, Soraia Nogueira…[et al.]. 2019. Impairment on Cardiopulmonary Function after Marathon: Role of Exhaled Nitric Oxide. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1203976
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sierra, Ana P. R.…[et al.]. Impairment on Cardiopulmonary Function after Marathon: Role of Exhaled Nitric Oxide. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1203976
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sierra, Ana P. R.& Oliveira-Junior, Manoel Carneiro& Almeida, Francine Maria& Benetti, Marino& Oliveira, Rodrigo A.& Felix, Soraia Nogueira…[et al.]. Impairment on Cardiopulmonary Function after Marathon: Role of Exhaled Nitric Oxide. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1203976
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203976
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر