Predictive Role of Serum Cytokine Profiles in Acute Kidney Injury after Living Donor Liver Transplantation
المؤلفون المشاركون
Chae, Min Suk
Kim, Youngchan
Chung, Hyun Sik
Park, Chul Soo
Lee, Jaemin
Choi, Jong Ho
Hong, Sang Hyun
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-01
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
Previous studies have shown that a higher serum interleukin- (IL-) 6 level is associated with a higher risk of acute kidney injury (AKI) development after major nontransplant surgery.
Our study investigated the potential association of preoperative serum cytokine profiles with new AKI development in patients who underwent living donor liver transplantation (LDLT).
Methods.
Serum levels of cytokines IL-2, IL-6, IL-10, IL-12, and IL-17, interferon-γ, and tumor necrosis factor- (TNF-) α were measured in 226 LDLT recipients preoperatively and analyzed retrospectively.
Recipients with a preoperative functional impairment of the kidney were excluded.
AKI was defined according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria.
Results.
In a univariate regression model, IL-6, IL-17, and TNF-α levels showed an association with AKI development after LDLT.
Multivariate analysis showed an independent association of the preoperative serum IL-6 level with AKI development after LDLT and a significant relationship between higher serum IL-6 levels and a greater likelihood of developing AKI.
Serum IL-6 levels were higher in patients with stage 3 AKI than in patients who did not develop AKI.
Conclusions.
Our results support the need for further investigations of IL-6 as a predictor of AKI development in patients undergoing LDLT.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chae, Min Suk& Kim, Youngchan& Chung, Hyun Sik& Park, Chul Soo& Lee, Jaemin& Choi, Jong Ho…[et al.]. 2018. Predictive Role of Serum Cytokine Profiles in Acute Kidney Injury after Living Donor Liver Transplantation. Mediators of Inflammation،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1204296
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chae, Min Suk…[et al.]. Predictive Role of Serum Cytokine Profiles in Acute Kidney Injury after Living Donor Liver Transplantation. Mediators of Inflammation No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1204296
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chae, Min Suk& Kim, Youngchan& Chung, Hyun Sik& Park, Chul Soo& Lee, Jaemin& Choi, Jong Ho…[et al.]. Predictive Role of Serum Cytokine Profiles in Acute Kidney Injury after Living Donor Liver Transplantation. Mediators of Inflammation. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1204296
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1204296
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر