Candidate Animal Disease Model of Elizabethkingia Spp. Infection in Humans, Based on the Systematic Pathology and Oxidative Damage Caused by E. miricola in Pelophylax nigromaculatus
المؤلفون المشاركون
Ou, Yangping
Geng, Yi
Feng, Yang
Huang, Xiaoli
Wang, Kaiyu
Chen, Defang
Yang, Shiyong
Tang, Hong
Xiong, Guanqing
Li, Liangyu
Yang, Yucen
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-09-18
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Most species of the genus Elizabethkingia are pathogenic to humans and animals, most commonly causing meningitis.
However, our understanding of the pathogenic mechanisms involved is poor and there have been few pathological studies of Elizabethkingia spp.
in animals.
To understand the host injury induced by Elizabethkingia spp., we established a model of E.
miricola infection in the black-spotted frog (Pelophylax nigromaculatus).
The systematic pathology in and oxidative damage in the infection model were investigated.
Our results show that recently isolated E.
miricola is a bacterium that mainly parasitizes the host brain and that neurogenic organs are the predominant sites of damage.
Infection mainly manifested as severe brain abscesses, meningoencephalitis, necrotic spondylitis, and necrotic retinitis.
The liver, spleen, kidney, gastrointestinal tract, and lung were also affected to varying degrees, with bacterial necrotic inflammation.
P.
nigromaculatus also suffered enormous damage to its oxidative system during E.
miricola infection, which may have further aggravated its disease state.
Our results provide a preliminary reference for the study and treatment of Elizabethkingia spp.-induced neurological diseases in animals.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Xiaoli& Feng, Yang& Tang, Hong& Xiong, Guanqing& Li, Liangyu& Yang, Yucen…[et al.]. 2019. Candidate Animal Disease Model of Elizabethkingia Spp. Infection in Humans, Based on the Systematic Pathology and Oxidative Damage Caused by E. miricola in Pelophylax nigromaculatus. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1204604
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Xiaoli…[et al.]. Candidate Animal Disease Model of Elizabethkingia Spp. Infection in Humans, Based on the Systematic Pathology and Oxidative Damage Caused by E. miricola in Pelophylax nigromaculatus. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1204604
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Xiaoli& Feng, Yang& Tang, Hong& Xiong, Guanqing& Li, Liangyu& Yang, Yucen…[et al.]. Candidate Animal Disease Model of Elizabethkingia Spp. Infection in Humans, Based on the Systematic Pathology and Oxidative Damage Caused by E. miricola in Pelophylax nigromaculatus. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1204604
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1204604
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر