Factors Associated with Mortality among Patients on TB Treatment in the Southern Region of Zimbabwe, 2013
المؤلفون المشاركون
Siziba, Nicholas
Sandy, Charles
Takarinda, Kudakwashe C.
Masuka, Nyasha
Hazangwe, Patrick
Choto, Regis C.
Mutasa-Apollo, Tsitsi
Nkomo, Brilliant
Sibanda, Edwin
Mugurungi, Owen
Harries, Anthony D.
المصدر
Tuberculosis Research and Treatment
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-03-02
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
In 2013, the tuberculosis (TB) mortality rate was highest in southern Zimbabwe at 16%.
We therefore sought to determine factors associated with mortality among registered TB patients in this region.
Methodology.
This was a retrospective record review of registered patients receiving anti-TB treatment in 2013.
Results.
Of 1,971 registered TB patients, 1,653 (84%) were new cases compared with 314 (16%) retreatment cases.
There were 1,538 (78%) TB/human immunodeficiency virus (HIV) coinfected patients, of whom 1,399 (91%) were on antiretroviral therapy (ART) with median pre-ART CD4 count of 133 cells/uL (IQR, 46–282).
Overall, 428 (22%) TB patients died.
Factors associated with increased mortality included being ≥65 years old [adjusted relative risk (ARR) = 2.48 (95% CI 1.35–4.55)], a retreatment TB case [ARR = 1.34 (95% CI, 1.10–1.63)], and being HIV-positive [ARR = 1.87 (95% CI, 1.44–2.42)] whilst ART initiation was protective [ARR = 0.25 (95% CI, 0.22–0.29)].
Cumulative mortality rates were 10%, 14%, and 21% at one, two, and six months, respectively, after starting TB treatment.
Conclusion.
There was high mortality especially in the first two months of anti-TB treatment, with risk factors being recurrent TB and being HIV-infected, despite a high uptake of ART.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Takarinda, Kudakwashe C.& Sandy, Charles& Masuka, Nyasha& Hazangwe, Patrick& Choto, Regis C.& Mutasa-Apollo, Tsitsi…[et al.]. 2017. Factors Associated with Mortality among Patients on TB Treatment in the Southern Region of Zimbabwe, 2013. Tuberculosis Research and Treatment،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1205253
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Takarinda, Kudakwashe C.…[et al.]. Factors Associated with Mortality among Patients on TB Treatment in the Southern Region of Zimbabwe, 2013. Tuberculosis Research and Treatment No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1205253
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Takarinda, Kudakwashe C.& Sandy, Charles& Masuka, Nyasha& Hazangwe, Patrick& Choto, Regis C.& Mutasa-Apollo, Tsitsi…[et al.]. Factors Associated with Mortality among Patients on TB Treatment in the Southern Region of Zimbabwe, 2013. Tuberculosis Research and Treatment. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1205253
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1205253
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر