![](/images/graphics-bg.png)
Quercetin Improving Lipid Metabolism by Regulating Lipid Metabolism Pathway of Ileum Mucosa in Broilers
المؤلفون المشاركون
Lu, Han
Wang, Mi
Wang, Shanshan
Mao, Yanjun
Ying, Linlin
Li, Yao
Wang, Bo
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-17، 17ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-18
دولة النشر
مصر
عدد الصفحات
17
التخصصات الرئيسية
الملخص EN
This study is aimed at evaluating the regulatory mechanism of quercetin on lipid metabolism in the ileum of broilers to better understand these pathways decreasing abdominal fat.
480 chickens were randomly divided into 4 groups (control, 0.02% quercetin, 0.04% quercetin, and 0.06% quercetin).
Breast muscle, thigh muscle, and abdominal fat pad were removed and weighed at 42 d of age.
Serum was obtained by centrifuging blood samples from the jugular vein (10 ml) to determine high-density lipoprotein (HDL), total cholesterol (TC), low-density lipoprotein (LDL), triglyceride (TG), leptin, and adiponectin using ELISA.
About 5 g of the ileum was harvested and immediately frozen in liquid nitrogen for RNA-seq.
Then, the confirmation of RNA-seq results by the Real-Time Quantitative PCR (RT-qPCR) method was evaluated using Pearson’s correlation.
Compared with control, abdominal fat percentage was significantly decreased with increasing quercetin supplementation, and the best result was obtained at 0.06% dietary quercetin supplementation (P<0.01).
Breast muscle percentage was significantly decreased at 0.02% quercetin (P<0.01), and thigh muscle percentage tended to increase (P=0.078).
Meanwhile, 0.04% and 0.06% quercetin significantly decreased TG (P<0.01), TC (P<0.01), and LDL content (P<0.05) in serum.
Serum leptin and adiponectin contents were significantly increased by 0.04% and 0.06% dietary quercetin supplementation, compared with the control (P<0.01).
Analyses of Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) database were used to identify differently expressed genes and lipid metabolism pathways.
Quercetin decreased abdominal fat percentage through regulating fat digestion and absorption, glycerophospholipid metabolism, AMPK signaling pathway, fatty acid degradation, and cholesterol metabolism.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Mi& Mao, Yanjun& Wang, Bo& Wang, Shanshan& Lu, Han& Ying, Linlin…[et al.]. 2020. Quercetin Improving Lipid Metabolism by Regulating Lipid Metabolism Pathway of Ileum Mucosa in Broilers. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-17.
https://search.emarefa.net/detail/BIM-1205675
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Mi…[et al.]. Quercetin Improving Lipid Metabolism by Regulating Lipid Metabolism Pathway of Ileum Mucosa in Broilers. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-17.
https://search.emarefa.net/detail/BIM-1205675
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Mi& Mao, Yanjun& Wang, Bo& Wang, Shanshan& Lu, Han& Ying, Linlin…[et al.]. Quercetin Improving Lipid Metabolism by Regulating Lipid Metabolism Pathway of Ileum Mucosa in Broilers. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-17.
https://search.emarefa.net/detail/BIM-1205675
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1205675
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)