Synergistic Effects of Human Platelet-Rich Plasma Combined with Adipose-Derived Stem Cells on Healing in a Mouse Pressure Injury Model
المؤلفون المشاركون
Xiao, Shune
Wei, Zairong
Deng, Chengliang
Wang, Dali
Liu, Zhiyuan
Tao, Kerong
Li, Hai
Jin, Wenhu
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-30
دولة النشر
مصر
عدد الصفحات
12
الملخص EN
Pressure injury (PI) affects quality of life and results in economic and social burdens.
Local transplantation of human adipose-derived stem cells (ASCs) is considered an effective treatment.
However, ASC suspension alone is vulnerable to the immune system and results in a shortened cell survival.
There is increasing evidence of a synergistic effect of platelet-rich plasma (PRP) combined with ASCs on wound healing.
This study investigated the effectiveness, synergy, and mechanism of wound healing following local injection of PRP combined with ASCs in a rodent PI model.
PRP or ASCs alone were the control intervention.
Wound healing, inflammatory infiltration, collagen deposition, angiogenesis, neurogenesis, and cell homing were investigated.
PI healing was promoted by the synergistic effects of PRP combined with ASCs.
The combination was more effective than ASCs alone for modulating inflammation, increasing collagen deposition, angiogenesis, neurogenesis, and the persistence of the injected ASCs.
These data provide a theoretical foundation for the clinical administration of ASCs combined with PRP in PI healing and skin regeneration.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Zhiyuan& Xiao, Shune& Tao, Kerong& Li, Hai& Jin, Wenhu& Wei, Zairong…[et al.]. 2019. Synergistic Effects of Human Platelet-Rich Plasma Combined with Adipose-Derived Stem Cells on Healing in a Mouse Pressure Injury Model. Stem Cells International،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1208594
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Zhiyuan…[et al.]. Synergistic Effects of Human Platelet-Rich Plasma Combined with Adipose-Derived Stem Cells on Healing in a Mouse Pressure Injury Model. Stem Cells International No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1208594
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Zhiyuan& Xiao, Shune& Tao, Kerong& Li, Hai& Jin, Wenhu& Wei, Zairong…[et al.]. Synergistic Effects of Human Platelet-Rich Plasma Combined with Adipose-Derived Stem Cells on Healing in a Mouse Pressure Injury Model. Stem Cells International. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1208594
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1208594
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر