Experimental Strategies of Mesenchymal Stem Cell Propagation: Adverse Events and Potential Risk of Functional Changes
المؤلفون المشاركون
Drela, Katarzyna
Nowakowski, Adam
Lukomska, Barbara
Stanaszek, Luiza
Kuczynska, Zuzanna
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-03-06
دولة النشر
مصر
عدد الصفحات
10
الملخص EN
Mesenchymal stem cells (MSCs) are attractive candidates for cell-based tissue repair approaches.
Hundreds of clinical trials using MSCs have been completed and many others are still being investigated.
For most therapeutic applications, MSC propagation in vitro is often required.
However, ex vivo culture condition is not fully physiological and may affect biological properties of MSCs including their regenerative potential.
Moreover, both cell cryopreservation and labelling procedure prior to infusion may have the negative impact on their expected effect in vivo.
The incidence of MSC transformation during in vitro culture should be also taken into consideration before using cells in stem cell therapy.
In our review, we focused on different aspects of MSC propagation that might influence their regenerative properties of MSC.
We also discussed the influence of different factors that might abolish MSC proliferation and differentiation as well as potential impact of stem cell senescence and aging.
Despite of many positive therapeutic effects of MSC therapy, one has to be conscious about potential cell changes that could appear during manufacturing of MSCs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Drela, Katarzyna& Stanaszek, Luiza& Nowakowski, Adam& Kuczynska, Zuzanna& Lukomska, Barbara. 2019. Experimental Strategies of Mesenchymal Stem Cell Propagation: Adverse Events and Potential Risk of Functional Changes. Stem Cells International،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1209417
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Drela, Katarzyna…[et al.]. Experimental Strategies of Mesenchymal Stem Cell Propagation: Adverse Events and Potential Risk of Functional Changes. Stem Cells International No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1209417
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Drela, Katarzyna& Stanaszek, Luiza& Nowakowski, Adam& Kuczynska, Zuzanna& Lukomska, Barbara. Experimental Strategies of Mesenchymal Stem Cell Propagation: Adverse Events and Potential Risk of Functional Changes. Stem Cells International. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1209417
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1209417
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر