Impaired Ability to Suppress Excitability of Antagonist Motoneurons at Onset of Dorsiflexion in Adults with Cerebral Palsy

المؤلفون المشاركون

Geertsen, Svend Sparre
Nielsen, Jens Bo
Kirk, Henrik

المصدر

Neural Plasticity

العدد

المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-11، 11ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2018-10-09

دولة النشر

مصر

عدد الصفحات

11

التخصصات الرئيسية

الأحياء
الطب البشري

الملخص EN

We recently showed that impaired gait function in adults with cerebral palsy (CP) is associated with reduced rate of force development in ankle dorsiflexors.

Here, we explore potential mechanisms.

We investigated the suppression of antagonist excitability, calculated as the amount of soleus H-reflex depression at the onset of ankle dorsiflexion compared to rest, in 24 adults with CP (34.3 years, range 18–57; GMFCS 1.95, range 1–3) and 15 healthy, age-matched controls.

Furthermore, the central common drive to dorsiflexor motoneurons during a static contraction in the two groups was examined by coherence analyses.

The H-reflex was significantly reduced by 37% at the onset of dorsiflexion compared to rest in healthy adults (P<0.001) but unchanged in adults with CP (P=0.91).

Also, the adults with CP had significantly less coherence.

These findings suggest that the ability to suppress antagonist motoneuronal excitability at movement onset is impaired and that the central common drive during static contractions is reduced in adults with CP.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Geertsen, Svend Sparre& Kirk, Henrik& Nielsen, Jens Bo. 2018. Impaired Ability to Suppress Excitability of Antagonist Motoneurons at Onset of Dorsiflexion in Adults with Cerebral Palsy. Neural Plasticity،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1209946

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Geertsen, Svend Sparre…[et al.]. Impaired Ability to Suppress Excitability of Antagonist Motoneurons at Onset of Dorsiflexion in Adults with Cerebral Palsy. Neural Plasticity No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1209946

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Geertsen, Svend Sparre& Kirk, Henrik& Nielsen, Jens Bo. Impaired Ability to Suppress Excitability of Antagonist Motoneurons at Onset of Dorsiflexion in Adults with Cerebral Palsy. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1209946

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1209946