Impaired Ability to Suppress Excitability of Antagonist Motoneurons at Onset of Dorsiflexion in Adults with Cerebral Palsy
Joint Authors
Geertsen, Svend Sparre
Nielsen, Jens Bo
Kirk, Henrik
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-09
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
We recently showed that impaired gait function in adults with cerebral palsy (CP) is associated with reduced rate of force development in ankle dorsiflexors.
Here, we explore potential mechanisms.
We investigated the suppression of antagonist excitability, calculated as the amount of soleus H-reflex depression at the onset of ankle dorsiflexion compared to rest, in 24 adults with CP (34.3 years, range 18–57; GMFCS 1.95, range 1–3) and 15 healthy, age-matched controls.
Furthermore, the central common drive to dorsiflexor motoneurons during a static contraction in the two groups was examined by coherence analyses.
The H-reflex was significantly reduced by 37% at the onset of dorsiflexion compared to rest in healthy adults (P<0.001) but unchanged in adults with CP (P=0.91).
Also, the adults with CP had significantly less coherence.
These findings suggest that the ability to suppress antagonist motoneuronal excitability at movement onset is impaired and that the central common drive during static contractions is reduced in adults with CP.
American Psychological Association (APA)
Geertsen, Svend Sparre& Kirk, Henrik& Nielsen, Jens Bo. 2018. Impaired Ability to Suppress Excitability of Antagonist Motoneurons at Onset of Dorsiflexion in Adults with Cerebral Palsy. Neural Plasticity،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1209946
Modern Language Association (MLA)
Geertsen, Svend Sparre…[et al.]. Impaired Ability to Suppress Excitability of Antagonist Motoneurons at Onset of Dorsiflexion in Adults with Cerebral Palsy. Neural Plasticity No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1209946
American Medical Association (AMA)
Geertsen, Svend Sparre& Kirk, Henrik& Nielsen, Jens Bo. Impaired Ability to Suppress Excitability of Antagonist Motoneurons at Onset of Dorsiflexion in Adults with Cerebral Palsy. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1209946
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1209946