Spatial Integration of Somatosensory Inputs during Sensory-Motor Plasticity Phenomena Is Normal in Focal Hand Dystonia

المؤلفون المشاركون

Quartarone, Angelo
Girlanda, Paolo
Terranova, C.
Rizzo, V.
Morgante, F.
Maggio, R.
Calamuneri, A.
Chillemi, G.

المصدر

Neural Plasticity

العدد

المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2018-10-10

دولة النشر

مصر

عدد الصفحات

7

التخصصات الرئيسية

الأحياء
الطب البشري

الملخص EN

Background.

Surround inhibition is a system that sharpens sensation by creating an inhibitory zone around the central core of activation.

In the motor system, this mechanism probably contributes to the selection of voluntary movements, and it seems to be lost in dystonia.

Objectives.

To explore if sensory information is abnormally processed and integrated in focal hand dystonia (FHD) and if surround inhibition phenomena are operating during sensory-motor plasticity and somatosensory integration in normal humans and in patients with FHD.

Methods.

We looked at the MEP facilitation obtained after 5 Hz repetitive paired associative stimulation of median (PAS M), ulnar (PAS U), and median + ulnar nerve (PAS MU) stimulation in 8 normal subjects and 8 FHD.

We evaluated the ratio MU/(M + U) ∗ 100 and the spatial and temporal somatosensory integration recording the somatosensory evoked potentials (SEPs) evoked by a dual nerve input.

Results.

FHD had two main abnormalities: first, the amount of facilitation was larger than normal subjects; second, the spatial specificity was lost.

The MU/(M + U) ∗ 100 ratio was similar in healthy subjects and in FHD patients, and the somatosensory integration was normal in this subset of patients.

Conclusions.

The inhibitory integration of somatosensory inputs and the somatosensory inhibition are normal in patients with focal dystonia as well as lateral surrounding inhibition phenomena during sensory-motor plasticity in FHD.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Terranova, C.& Rizzo, V.& Morgante, F.& Maggio, R.& Calamuneri, A.& Chillemi, G.…[et al.]. 2018. Spatial Integration of Somatosensory Inputs during Sensory-Motor Plasticity Phenomena Is Normal in Focal Hand Dystonia. Neural Plasticity،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1210077

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Terranova, C.…[et al.]. Spatial Integration of Somatosensory Inputs during Sensory-Motor Plasticity Phenomena Is Normal in Focal Hand Dystonia. Neural Plasticity No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1210077

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Terranova, C.& Rizzo, V.& Morgante, F.& Maggio, R.& Calamuneri, A.& Chillemi, G.…[et al.]. Spatial Integration of Somatosensory Inputs during Sensory-Motor Plasticity Phenomena Is Normal in Focal Hand Dystonia. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1210077

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1210077