Spatial Integration of Somatosensory Inputs during Sensory-Motor Plasticity Phenomena Is Normal in Focal Hand Dystonia
Joint Authors
Quartarone, Angelo
Girlanda, Paolo
Terranova, C.
Rizzo, V.
Morgante, F.
Maggio, R.
Calamuneri, A.
Chillemi, G.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Surround inhibition is a system that sharpens sensation by creating an inhibitory zone around the central core of activation.
In the motor system, this mechanism probably contributes to the selection of voluntary movements, and it seems to be lost in dystonia.
Objectives.
To explore if sensory information is abnormally processed and integrated in focal hand dystonia (FHD) and if surround inhibition phenomena are operating during sensory-motor plasticity and somatosensory integration in normal humans and in patients with FHD.
Methods.
We looked at the MEP facilitation obtained after 5 Hz repetitive paired associative stimulation of median (PAS M), ulnar (PAS U), and median + ulnar nerve (PAS MU) stimulation in 8 normal subjects and 8 FHD.
We evaluated the ratio MU/(M + U) ∗ 100 and the spatial and temporal somatosensory integration recording the somatosensory evoked potentials (SEPs) evoked by a dual nerve input.
Results.
FHD had two main abnormalities: first, the amount of facilitation was larger than normal subjects; second, the spatial specificity was lost.
The MU/(M + U) ∗ 100 ratio was similar in healthy subjects and in FHD patients, and the somatosensory integration was normal in this subset of patients.
Conclusions.
The inhibitory integration of somatosensory inputs and the somatosensory inhibition are normal in patients with focal dystonia as well as lateral surrounding inhibition phenomena during sensory-motor plasticity in FHD.
American Psychological Association (APA)
Terranova, C.& Rizzo, V.& Morgante, F.& Maggio, R.& Calamuneri, A.& Chillemi, G.…[et al.]. 2018. Spatial Integration of Somatosensory Inputs during Sensory-Motor Plasticity Phenomena Is Normal in Focal Hand Dystonia. Neural Plasticity،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1210077
Modern Language Association (MLA)
Terranova, C.…[et al.]. Spatial Integration of Somatosensory Inputs during Sensory-Motor Plasticity Phenomena Is Normal in Focal Hand Dystonia. Neural Plasticity No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1210077
American Medical Association (AMA)
Terranova, C.& Rizzo, V.& Morgante, F.& Maggio, R.& Calamuneri, A.& Chillemi, G.…[et al.]. Spatial Integration of Somatosensory Inputs during Sensory-Motor Plasticity Phenomena Is Normal in Focal Hand Dystonia. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1210077
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210077