Protective Effect of Ginkgo biloba and Magnetized Water on Nephropathy in Induced Type 2 Diabetes in Rat
المؤلفون المشاركون
Zayed, Ahmed E.
Saleh, Ahmed
Gomaa, Asmaa M. S.
Abd-Elkareem, Mahmoud
Anwar, Mamdouh M.
Hassanein, Khaled M. A.
Elsherbiny, Mohsen M.
Kotb, Ahmed M.
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-11
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
We aimed in our current study to explore the protective effect of Ginkgo biloba (GB) and magnetized water (MW) against nephrotoxicity associating induced type 2 diabetes mellitus in rat.
Here, we induced diabetes by feeding our lab rats on a high fat-containing diet (4 weeks) and after that injecting them with streptozotocin (STZ).
We randomly divided forty rats into four different groups: nontreated control (Ctrl), nontreated diabetic (Diabetic), Diabetic+GB (4-week treatment), and Diabetic+MW (4-week treatment).
After the experiment was finished, serum and kidney tissue samples were gathered.
Blood levels of glucose, triglycerides, cholesterol, creatinine, and urea were markedly elevated in the diabetic group than in the control group.
In all animals treated with GB and MW, the levels of urea, creatinine, and glucose were significantly reduced (all P<0.01).
GB and MW attenuated glomerular and tubular injury as well as the histological score.
Furthermore, they normalized the contents of glutathione reductase and SOD2.
In summary, our data showed that GB and MW treatment protected type 2 diabetic rat kidneys from nephrotoxic damages by reducing the hyperlipidemia, uremia, oxidative stress, and renal dysfunction.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zayed, Ahmed E.& Saleh, Ahmed& Gomaa, Asmaa M. S.& Abd-Elkareem, Mahmoud& Anwar, Mamdouh M.& Hassanein, Khaled M. A.…[et al.]. 2018. Protective Effect of Ginkgo biloba and Magnetized Water on Nephropathy in Induced Type 2 Diabetes in Rat. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1210918
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zayed, Ahmed E.…[et al.]. Protective Effect of Ginkgo biloba and Magnetized Water on Nephropathy in Induced Type 2 Diabetes in Rat. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1210918
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zayed, Ahmed E.& Saleh, Ahmed& Gomaa, Asmaa M. S.& Abd-Elkareem, Mahmoud& Anwar, Mamdouh M.& Hassanein, Khaled M. A.…[et al.]. Protective Effect of Ginkgo biloba and Magnetized Water on Nephropathy in Induced Type 2 Diabetes in Rat. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1210918
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1210918
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر