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Anticancer Properties of Graviola (Annona muricata): A Comprehensive Mechanistic Review
المؤلفون المشاركون
Rady, Islam
Bloch, Melissa B.
Chamcheu, Roxane-Cherille N.
Banang Mbeumi, Sergette
Anwar, Md Rafi
Mohamed, Hadir
Kuiate, Jules-Roger
Noubissi, Felicite K.
Whitfield, G. Kerr
Chamcheu, Jean Christopher
El Sayed, Khalid
Babatunde, A. S.
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-39، 39ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-30
دولة النشر
مصر
عدد الصفحات
39
التخصصات الرئيسية
الملخص EN
Graviola (Annona muricata) is a small deciduous tropical evergreen fruit tree, belonging to the Annonaceae family, and is widely grown and distributed in tropical and subtropical regions around the world.
The aerial parts of graviola have several functions: the fruits have been widely used as food confectionaries, while several preparations, especially decoctions of the bark, fruits, leaves, pericarp, seeds, and roots, have been extensively used in traditional medicine to treat multiple ailments including cancers by local communities in tropical Africa and South America.
The reported therapeutic benefits of graviola against various human tumors and disease agents in in vitro culture and preclinical animal model systems are typically tested for their ability to specifically target the disease, while exerting little or no effect on normal cell viability.
Over 212 phytochemical ingredients have been reported in graviola extracts prepared from different plant parts.
The specific bioactive constituents responsible for the major anticancer, antioxidant, anti-inflammatory, antimicrobial, and other health benefits of graviola include different classes of annonaceous acetogenins (metabolites and products of the polyketide pathway), alkaloids, flavonoids, sterols, and others.
This review summarizes the current understanding of the anticancer effects of A.
muricata and its constituents on diverse cancer types and disease states, as well as efficacy and safety concerns.
It also includes discussion of our current understanding of possible mechanisms of action, with the hope of further stimulating the development of improved and affordable therapies for a variety of ailments.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rady, Islam& Bloch, Melissa B.& Chamcheu, Roxane-Cherille N.& Banang Mbeumi, Sergette& Anwar, Md Rafi& Mohamed, Hadir…[et al.]. 2018. Anticancer Properties of Graviola (Annona muricata): A Comprehensive Mechanistic Review. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-39.
https://search.emarefa.net/detail/BIM-1210928
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rady, Islam…[et al.]. Anticancer Properties of Graviola (Annona muricata): A Comprehensive Mechanistic Review. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-39.
https://search.emarefa.net/detail/BIM-1210928
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rady, Islam& Bloch, Melissa B.& Chamcheu, Roxane-Cherille N.& Banang Mbeumi, Sergette& Anwar, Md Rafi& Mohamed, Hadir…[et al.]. Anticancer Properties of Graviola (Annona muricata): A Comprehensive Mechanistic Review. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-39.
https://search.emarefa.net/detail/BIM-1210928
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1210928
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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