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Antihypertensive Effect of Ethanolic Extract from Acanthopanax sessiliflorus Fruits and Quality Control of Active Compounds
المؤلفون المشاركون
Jung, In Ho
Kim, Sung Eun
Lee, Yeong-Geun
Kim, Dae Hyun
Kim, Haneul
Kim, Geum-Soog
Baek, Nam-In
Lee, Dae Young
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-23
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Acanthopanax sessiliflorus (Rupr.
& Maxim.) Seem., which belongs to the Araliaceae family, mainly inhabits Korea, China, and Japan.
Traditionally, Acanthopanax species have been used as treatment for several diseases such as diabetes, tumors, and rheumatoid arthritis.
Especially, its fruits have many biological functions including antitumor, immunostimulating, antithrombosis, and antiplatelet activities.
Recently, the extract of A.
sessiliflorus fruit has been reported to have antithrombotic and antiplatelet activities related to the alleviation of hypertension.
Therefore, we investigated the antihypertensive effect of ethanolic extract from A.
sessiliflorus fruits (DHP1501) through in vivo, ex vivo, and in vitro studies.
In this study, DHP1501 demonstrated free radical scavenging capacity, enhanced endothelial nitric oxide (NO) production, and inhibited angiotensin-converting enzyme (ACE) activity in spontaneously hypertensive rats (SHRs), resulting in the improvement of vascular relaxation and decrease in blood pressure in the hypertensive animal model.
These results suggest that A.
sessiliflorus fruit extract may be a promising functional material for the prevention and treatment of hypertension.
Furthermore, this study demonstrated the utility of MS-based active compounds for the quality control of DHP1501.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jung, In Ho& Kim, Sung Eun& Lee, Yeong-Geun& Kim, Dae Hyun& Kim, Haneul& Kim, Geum-Soog…[et al.]. 2018. Antihypertensive Effect of Ethanolic Extract from Acanthopanax sessiliflorus Fruits and Quality Control of Active Compounds. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1211578
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jung, In Ho…[et al.]. Antihypertensive Effect of Ethanolic Extract from Acanthopanax sessiliflorus Fruits and Quality Control of Active Compounds. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-14.
https://search.emarefa.net/detail/BIM-1211578
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jung, In Ho& Kim, Sung Eun& Lee, Yeong-Geun& Kim, Dae Hyun& Kim, Haneul& Kim, Geum-Soog…[et al.]. Antihypertensive Effect of Ethanolic Extract from Acanthopanax sessiliflorus Fruits and Quality Control of Active Compounds. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1211578
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1211578
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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