Effects of Redox Disturbances on Intestinal Contractile Reactivity in Rats Fed with a Hypercaloric Diet
المؤلفون المشاركون
Diniz, Anderson Fellyp Avelino
dos Santos Ferreira, Elba
de Lima Tavares Toscano, Lydiane
Silva, Alexandre Sérgio
da Silva, Bagnólia Araújo
Queiroga, Fernando R.
da Silva, Patrícia M.
Cavalcante, Fabiana de A.
de Souza, Iara L. L.
Carvalho, Maria Thaynan de L.
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-10-25
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Few studies have associated the effects of changes in caloric intake and redox disturbances in the gastrointestinal tract.
Therefore, the present study aimed at evaluating the hypercaloric diet consumption influence on the contractile reactivity of intestinal smooth muscle, morphology, and oxidative stress of rat ileum.
Wistar rats were randomly divided into groups that received a standard diet and fed with a hypercaloric diet for 8 weeks.
Animals were euthanized, and the ileum was isolated to isotonic contraction monitoring.
Morphology was evaluated by histological staining and oxidative stress by quantification of malondialdehyde levels and total antioxidant activity.
Cumulative concentration-response curves to KCl and carbachol were attenuated in rats fed with a hypercaloric diet compared to those that received a standard diet.
In addition, an increase in caloric intake promotes a rise in the thickness of the longitudinal smooth muscle layer of rat ileum and tissue malondialdehyde levels, characterizing lipid peroxidation, as well as a decrease in the antioxidant activity.
Thus, it was concluded that the consumption of a hypercaloric diet impairs rat intestinal contractility due to mechanisms involving modifications in the intestinal smooth muscle architecture triggered by redox disturbances.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
de Souza, Iara L. L.& dos Santos Ferreira, Elba& Diniz, Anderson Fellyp Avelino& Carvalho, Maria Thaynan de L.& Queiroga, Fernando R.& de Lima Tavares Toscano, Lydiane…[et al.]. 2018. Effects of Redox Disturbances on Intestinal Contractile Reactivity in Rats Fed with a Hypercaloric Diet. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1211790
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
de Souza, Iara L. L.…[et al.]. Effects of Redox Disturbances on Intestinal Contractile Reactivity in Rats Fed with a Hypercaloric Diet. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1211790
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
de Souza, Iara L. L.& dos Santos Ferreira, Elba& Diniz, Anderson Fellyp Avelino& Carvalho, Maria Thaynan de L.& Queiroga, Fernando R.& de Lima Tavares Toscano, Lydiane…[et al.]. Effects of Redox Disturbances on Intestinal Contractile Reactivity in Rats Fed with a Hypercaloric Diet. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1211790
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1211790
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر