Efficacy and Safety of Botulinum Toxin Type A in Treating Patients of Advanced Age with Idiopathic Trigeminal Neuralgia
المؤلفون المشاركون
Luo, Wei-Feng
Liu, Jing
Xu, Ying-Ying
Zhang, Qi-Lin
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-05
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objective.
To assess the therapeutic efficacy and safety of botulinum toxin type A (BTX-A) for treating idiopathic trigeminal neuralgia (ITN) in patients ≥80 years old.
Methods.
Selected patients n=43 with ITN, recruited from the neurology clinic and inpatient department of the Second Affiliated Hospital of Soochow University between August 2008 and February 2014, were grouped by age, one subset n=14 ≥80 years old and another n=29 <60 years old.
Each group scored similarly in degrees of pain registered by the visual analogue scale (VAS).
Dosing, efficacy, and safety of BTX-A injections were compared by group.
Results.
Mean dosages of BTX-A were 91.3 ± 25.6 U and 71.8 ± 33.1 U in older and younger patients, respectively t=1.930, p=0.061.
The median of the VAS score in older patients at baseline (8.5) declined significantly at 1 month after treatment (4.5) p=0.007, as did that of younger patients (8.0 and 5.0, resp.) p=0.001.
The median of the D values of the VAS scores did not differ significantly by group (older, 2.5; younger, 0; Z=−1.073, p=0.283).
Two patients in each group developed minor transient side effects p=0.825.
Adverse reactions in both groups were mild, resolving spontaneously within 3 weeks.
Conclusions.
BTX-A is effective and safe in treating patients of advanced age (≥80 years old) with ITN, at dosages comparable to those used in much younger counterparts (<60 years old).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Jing& Xu, Ying-Ying& Zhang, Qi-Lin& Luo, Wei-Feng. 2018. Efficacy and Safety of Botulinum Toxin Type A in Treating Patients of Advanced Age with Idiopathic Trigeminal Neuralgia. Pain Research and Management،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1212601
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Jing…[et al.]. Efficacy and Safety of Botulinum Toxin Type A in Treating Patients of Advanced Age with Idiopathic Trigeminal Neuralgia. Pain Research and Management No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1212601
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Jing& Xu, Ying-Ying& Zhang, Qi-Lin& Luo, Wei-Feng. Efficacy and Safety of Botulinum Toxin Type A in Treating Patients of Advanced Age with Idiopathic Trigeminal Neuralgia. Pain Research and Management. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1212601
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1212601
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر