Influence of Chronic Alcohol Use on Osteoblastic Differentiation of Bone Marrow Cells, Bone Properties, and Hepatic and Renal Morphology of Rats
المؤلفون المشاركون
Oliveira, L. D.
Cardoso de Sousa, Michelle
Vegian, Mariana Raquel da Cruz
Biserra, Matheus Alves
Costa, Bruno César Almeida
Camargo, Samira Esteves Afonso
Rode, Sigmar de Mello
Ramos, Carolina Judica
Vasconcellos, Luana Marotta Reis de
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Chronic alcohol exposure can affect the osteoblastic activity and the proliferation and differentiation of cells due to its toxic effect, which can affect negatively bone repair and bone microarchitecture.
The aim of this study was to evaluate the effects of chronic use of 20% alcohol on rats regarding osteoblastic differentiation, extrinsic and intrinsic properties of the tibia, and hepatic and renal morphology.
Wistar rats were divided into three groups (n=9) in accordance with a 24-week diet.
After euthanasia, kidneys, liver, and tibias were removed for analysis and femurs mesenchymal cells were collected.
The results showed that chronic use of 20% alcohol influenced neither the alkaline phosphatase production nor total protein (p>0.05) in rats, with similar formation of nodules in all groups (p>0.05).
However, significant changes in the liver and kidneys and adverse effects on the mechanical properties of the tibia were observed.
According to the results, it can be concluded that the chronic use of alcohol for 24 weeks had no negative influence on the activity and differentiation of osteoblasts, but the mechanical properties of the tibia were impaired and the organs responsible for metabolism and excretion were also affected due to the consumption of alcohol.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cardoso de Sousa, Michelle& Vegian, Mariana Raquel da Cruz& Biserra, Matheus Alves& Costa, Bruno César Almeida& Camargo, Samira Esteves Afonso& Rode, Sigmar de Mello…[et al.]. 2018. Influence of Chronic Alcohol Use on Osteoblastic Differentiation of Bone Marrow Cells, Bone Properties, and Hepatic and Renal Morphology of Rats. The Scientific World Journal،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1215609
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cardoso de Sousa, Michelle…[et al.]. Influence of Chronic Alcohol Use on Osteoblastic Differentiation of Bone Marrow Cells, Bone Properties, and Hepatic and Renal Morphology of Rats. The Scientific World Journal No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1215609
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cardoso de Sousa, Michelle& Vegian, Mariana Raquel da Cruz& Biserra, Matheus Alves& Costa, Bruno César Almeida& Camargo, Samira Esteves Afonso& Rode, Sigmar de Mello…[et al.]. Influence of Chronic Alcohol Use on Osteoblastic Differentiation of Bone Marrow Cells, Bone Properties, and Hepatic and Renal Morphology of Rats. The Scientific World Journal. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1215609
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1215609
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر