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Pharmacological Evaluation of Selected Medicinal Plants Used in the Management of Oral and Skin Infections in Ebem-Ohafia District, Abia State, Nigeria
المؤلفون المشاركون
Oyedemi, Sunday O.
Oyedemi, Blessing O.
Chibuzor, Johnson V.
Ijeh, Ifeoma I.
Coopoosamy, Roger M.
Aiyegoro, Ayobami O.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-04
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Oral and skin infections contribute significantly to the global health challenges responsible for the current trend of increased morbidity and premature death.
The purpose of this study was to document medicinal plants used in the management of oral and skin infections in Ebem-Ohafia Local Government Area (LGA), Abia State, and to characterize the in vitro antioxidant and antibacterial activity.
The thin layer chromatography (TLC) profiling of ten of the selected folklore medicine was carried out using a various solvent system of different polarity index.
The antioxidant capacity of the plant extracts was evaluated using chemical-based methods, and its antibacterial effect was investigated using disc diffusion and microdilution methods.
Sixty-one plant species belonging to 26 families were discovered, and the most frequently cited species are Euphorbiaceae (18.03%), Fabaceae (11.47%), and Asteraceae (11.47%).
All the plant extracts showed a promising free radical scavenging activity and efficient ferric reducing antioxidant power in a concentration-dependent manner possibly due to their richness in polyphenol with TLC profiling showing maximum three bands of phytochemicals.
Also, the plant extracts exhibited a mild to weak antibacterial activity against our panel of bacterial strains having MIC values ranging from 256 to > 512 μg/ mL reflected in their zone of inhibition at 10 μg/disc.
The data obtained for Breynia nivosa (BN), Eleusine indica (EI), Cassia alata (CA), Chromolaena odorata (CO), and Acalypha hispida (AH) extracts substantiate the traditional use of these herbal remedies in the region and open the possibility for the development of cheaper and affordable drugs in the treatment of oral and skin infections.
Further studies are needed to identify active ingredient with strong antibacterial and antioxidant capacities along with their molecular mechanisms.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Oyedemi, Blessing O.& Oyedemi, Sunday O.& Chibuzor, Johnson V.& Ijeh, Ifeoma I.& Coopoosamy, Roger M.& Aiyegoro, Ayobami O.. 2018. Pharmacological Evaluation of Selected Medicinal Plants Used in the Management of Oral and Skin Infections in Ebem-Ohafia District, Abia State, Nigeria. The Scientific World Journal،Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1215625
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Oyedemi, Blessing O.…[et al.]. Pharmacological Evaluation of Selected Medicinal Plants Used in the Management of Oral and Skin Infections in Ebem-Ohafia District, Abia State, Nigeria. The Scientific World Journal No. 2018 (2018), pp.1-16.
https://search.emarefa.net/detail/BIM-1215625
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Oyedemi, Blessing O.& Oyedemi, Sunday O.& Chibuzor, Johnson V.& Ijeh, Ifeoma I.& Coopoosamy, Roger M.& Aiyegoro, Ayobami O.. Pharmacological Evaluation of Selected Medicinal Plants Used in the Management of Oral and Skin Infections in Ebem-Ohafia District, Abia State, Nigeria. The Scientific World Journal. 2018. Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1215625
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1215625
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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