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Factors Influencing Hemoglobin Variability and Its Association with Mortality in Hemodialysis Patients
المؤلفون المشاركون
Sezer, Siren
Erkmen Uyar, Mehtap
Tutal, Emre
Bal, Zeynep
Demirci, Bahar Gurlek
Karakose, Suleyman
Acar, Nurhan Ozdemir
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-01
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Purpose.
We aimed to investigate the factors influencing hemoglobin variability with inflammatory and nutritional parameters and its associations with all-cause mortality among hemodialysis patients.
Methods.
One hundred and sixty-nine patients during the entire 12 months were enrolled into the study.
Fasting plasma glucose, creatinine, calcium, phosphorus, alkaline phosphatase, parathyroid hormone (PTH), C-reactive protein (CRP), serum iron, serum iron-binding capacity, and transferrin saturation were analyzed.
We defined six groups: low, target range, high, low-amplitude fluctuation with low hemoglobin levels, low-amplitude fluctuation with high hemoglobin levels, and high-amplitude fluctuation.
Body mass index (BMI), malnutrition-inflammation score (MIS), and Charlson Comorbidity Index were evaluated.
Results.
Hemoglobin variability was significantly correlated with age, platelet count, and number of hospitalization instances and inversely correlated with erythropoietin dose per body surface area.
The coefficient of variation of hemoglobin showed a correlation with MIS and ferritin.
The absolute level of hemoglobin showed a negative correlation between PTH, CRP, MIS, number of hospitalization instances and a positive correlation with albumin and BMI.
High, low, and target-range groups showed survival advantage compared to the other three groups.
In regression analysis, age, CRP levels, MIS, and BMI were the predictors of mortality.
Conclusion.
Inflammation and duration of anemia were the major predictors of hemoglobin variability.
High-amplitude fluctuation predicts high mortality; on the contrary low-amplitude fluctuations is related to better survival.
MIS was independently associated with mortality.
This trial is registered with NCT03454906.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bal, Zeynep& Demirci, Bahar Gurlek& Karakose, Suleyman& Tutal, Emre& Erkmen Uyar, Mehtap& Acar, Nurhan Ozdemir…[et al.]. 2018. Factors Influencing Hemoglobin Variability and Its Association with Mortality in Hemodialysis Patients. The Scientific World Journal،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1215664
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bal, Zeynep…[et al.]. Factors Influencing Hemoglobin Variability and Its Association with Mortality in Hemodialysis Patients. The Scientific World Journal No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1215664
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bal, Zeynep& Demirci, Bahar Gurlek& Karakose, Suleyman& Tutal, Emre& Erkmen Uyar, Mehtap& Acar, Nurhan Ozdemir…[et al.]. Factors Influencing Hemoglobin Variability and Its Association with Mortality in Hemodialysis Patients. The Scientific World Journal. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1215664
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1215664
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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