Study the effect of leaves and fruits of Figs (Ficuscarica, L.)‎ and olive (Oleaeuropaea, L.)‎ on obesity and kidney disorder rats

الملخص EN

The Effect of leaves and fruitsof figs (Ficuscarica, L.

) and olive (Oleaeuropaea, L.

) on obesity and kidney disorder rats were studied.

Sixty six adult male albino rats of sprague-dawely weighting (150-160g), All rats fed on a basal diet for 7days to make adjustment and then divided into three main groups as the following: The first main group (6 rats) (Group (1)): fed on basal diet as a control negative group, The second main group (30 rats): fed on the high fat diet with saturated fats to induce obesity and then divided to five subgroups each 6 rats, thesefed on high fat diet as a control positivegroup, other groupratsfed on 5% from olive (Oleaeurpaea)leaves, rats fed on 5% from figs (ficuscarica) leaves, rats fed on 5% from olive fruits and ratsfed on 5% from fig fruits.

The third main group (30 rats): rats injected with gentamicin (100mg/kg/day) to induce impaired kidney rats and then divided to subgroups each 6 rats, these rats with impaired kidney fed on basal diet as a control positive group, rats with impaired kidney and fed on 5% fromolive leaves, ratsfed on 5% from fig leaves, rats fed on 5% from olive fruits and ratsfed on 5% fromfigfruits.

Administration of leaves and fruits of figs (Ficuscarica L.

) and Olive (Oleaeuropaea, L.

) on obesity rats at 5% lowered the concentrations of total cholesterol, triglycerides, LDL-c, VLDL-c and decreased of urea, creatinine and uric acid.

On the other side, HDL-c was significanlyincreased.

Histopathological examination showed amelioration ofhistopathological lesions seen in kidney of kidney disorderrats when received the leaves and fruits of figs (Ficuscarica L.

) and Olive (Oleaeuropaea, L.

).

So, from this study itcan be concluded that intake of fruit and seeds powder of figs (Ficuscarica L.

) and Olive (Oleaeuropaea, L.

) especially at 5% can be useful for treating obesity and kidney disorder rats.