Histopathological and biochemical studies on the effect of green tea extract and vitamin c against fenitrothion toxicity in male albino rats
المؤلفون المشاركون
Tahun, Inas Abd al-Aziz
Muhammad, Rasha Salih
Dunya, Jihad Rashid
المصدر
Alexandria Journal of Veterinary Sciences
العدد
المجلد 57، العدد 1 (30 إبريل/نيسان 2018)، ص ص. 68-80، 13ص.
الناشر
جامعة الإسكندرية كلية الطب البيطري
تاريخ النشر
2018-04-30
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
This study aimed to evaluate the effect of green tea extract (GTE) and vitamin C as antioxidants on the biochemical oxidative stress parameters and histopathological changes induced by fenitrothion (FNT) pesticide in liver and kidney of albino rats.
Twenty-four rats were divided into four groups; group one (control), group two received 10 mg/kg b.wt.
of FNT orally, group three received FNT daily plus green tea extract at a concentration of 3% w/v and group four received FNT daily plus vitamin C at a concentration of 2 g ascorbic acid (vitamin C) /1 L.
The experiment was conducted for six weeks.
Blood samples were taken for biochemical parameters.
The histopathological studies were carried out on liver and kidney tissues at the end of the experiment.
Damage in the tissue samples was observed and confirmed with elevation of oxidative stress marker malondialdehyde (MDA).
Exposure of rats to fenitrothion induced significant increase of MDA and decrease in the values of SOD, GSH, CAT, TAC compared to control one in both serum and tissues samples.
However, administration of green tea and vitamin C to FNT treated group decreased in the values of MDA and improved the values of SOD (superoxide dismutase), GSH (glutathione) and CAT (catalase) toward the control values in both serum and tissues but could not normalize it.
Total antioxidant capacity (TAC) level showed a significant increase with FNT plus vitamin C and the FNT plus GTE treated groups compared to the FNT group.
Green tea and vitamin C, probably due to their strong antioxidant properties could improve and partially counteracts the toxic effect of FNT on oxidative stress parameters and repair the destructive effects of its damage in rat's liver and kidney tissues especially with GTE treated groups.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tahun, Inas Abd al-Aziz& Muhammad, Rasha Salih& Dunya, Jihad Rashid. 2018. Histopathological and biochemical studies on the effect of green tea extract and vitamin c against fenitrothion toxicity in male albino rats. Alexandria Journal of Veterinary Sciences،Vol. 57, no. 1, pp.68-80.
https://search.emarefa.net/detail/BIM-1330069
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tahun, Inas Abd al-Aziz…[et al.]. Histopathological and biochemical studies on the effect of green tea extract and vitamin c against fenitrothion toxicity in male albino rats. Alexandria Journal of Veterinary Sciences Vol. 57, no. 1 (Apr. 2018), pp.68-80.
https://search.emarefa.net/detail/BIM-1330069
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tahun, Inas Abd al-Aziz& Muhammad, Rasha Salih& Dunya, Jihad Rashid. Histopathological and biochemical studies on the effect of green tea extract and vitamin c against fenitrothion toxicity in male albino rats. Alexandria Journal of Veterinary Sciences. 2018. Vol. 57, no. 1, pp.68-80.
https://search.emarefa.net/detail/BIM-1330069
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 78-80
رقم السجل
BIM-1330069
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر