Acute kidney injuries in children with severe malaria : a comparative study of diagnostic criteria based on serum cystatin C and creatinine levels
العناوين الأخرى
إصابات الكلى الحادة عند الأطفال المصابين بملاريا حادة : دراسة مقارنة للمعايير التشخيصية المبنية على قياس تركيزي السيستاتين سي و الكرياتنين في مصل الدم
المؤلفون المشاركون
Afolayan, Folake Moriliat
Adedoyin, Olanrewaju Timothy
Abd al-Qadir, Muhammad Baba
Ibrahim, Olayinka Rashid
Biliaminu, Sikiru A.
Mokuolu, Olugbenga A.
Ojuawo, Ayodele
المصدر
Sultan Qaboos University Medical Journal
العدد
المجلد 20، العدد 4 (30 نوفمبر/تشرين الثاني 2020)، ص ص. 312-317، 6ص.
الناشر
جامعة السلطان قابوس كلية الطب و العلوم الصحية
تاريخ النشر
2020-11-30
دولة النشر
سلطنة عمان
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives: Serum creatinine levels are often used to diagnose acute kidney injury (AKI), but may not necessarily accurately reflect changes in glomerular filtration rate (GFR).
This study aimed to compare the prevalence of AKI in children with severe malaria using diagnostic criteria based on creatinine values in contrast to cystatin C.
Methods: This prospective cross-sectional study was performed between June 2016 and May 2017 at the University of Ilorin Teaching Hospital, Ilorin, Nigeria.
A total of 170 children aged 0.5–14 years old with severe malaria were included.
Serum cystatin C levels were determined using a particle-enhanced immunoturbidmetric assay method, while creatinine levels were measured using the Jaffe reaction.
Renal function assessed using cystatin C-derived estimated GFR (eGFR) was compared to that measured using three sets of criteria based on creatinine values including the Kidney Disease: Improved Global Outcomes (KDIGO) and World Health Organization (WHO) criteria as well as an absolute creatinine cut-off value of >1.5 mg/dL.
Results: Mean serum cystatin C and creatinine levels were 1.77 ± 1.37 mg/L and 1.23 ± 1.80 mg/dL, respectively (P = 0.002).
According to the KDIGO, WHO and absolute creatinine criteria, the frequency of AKI was 32.4%, 7.6% and 16.5%, respectively.
In contrast, the incidence of AKI based on cystatin C-derived eGFR was 51.8%.
Overall, the rate of detection of AKI was significantly higher using cystatin C compared to the KDIGO, WHO and absolute creatinine criteria (P = 0.003, <0.001 and <0.001, respectively).
Conclusion: Diagnostic criteria for AKI based on creatinine values may not indicate the actual burden of disease in children with severe malaria.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Afolayan, Folake Moriliat& Adedoyin, Olanrewaju Timothy& Abd al-Qadir, Muhammad Baba& Ibrahim, Olayinka Rashid& Biliaminu, Sikiru A.& Mokuolu, Olugbenga A.…[et al.]. 2020. Acute kidney injuries in children with severe malaria : a comparative study of diagnostic criteria based on serum cystatin C and creatinine levels. Sultan Qaboos University Medical Journal،Vol. 20, no. 4, pp.312-317.
https://search.emarefa.net/detail/BIM-1342892
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Afolayan, Folake Moriliat…[et al.]. Acute kidney injuries in children with severe malaria : a comparative study of diagnostic criteria based on serum cystatin C and creatinine levels. Sultan Qaboos University Medical Journal Vol. 20, no. 4 (Nov. 2020), pp.312-317.
https://search.emarefa.net/detail/BIM-1342892
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Afolayan, Folake Moriliat& Adedoyin, Olanrewaju Timothy& Abd al-Qadir, Muhammad Baba& Ibrahim, Olayinka Rashid& Biliaminu, Sikiru A.& Mokuolu, Olugbenga A.…[et al.]. Acute kidney injuries in children with severe malaria : a comparative study of diagnostic criteria based on serum cystatin C and creatinine levels. Sultan Qaboos University Medical Journal. 2020. Vol. 20, no. 4, pp.312-317.
https://search.emarefa.net/detail/BIM-1342892
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 317
رقم السجل
BIM-1342892
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر