Pregnancy outcomes in systemic lupus erythematosus women : a single tertiary centre experience
المؤلفون المشاركون
Hasan, Batul Ali
Salman, Bushra
al-Rashidi, Amani
al-Haddabi, Rahmah
al-Dughaishi, Tamima
al-Riyami, Nihal
المصدر
Sultan Qaboos University Medical Journal
العدد
المجلد 21، العدد 2 (31 مايو/أيار 2021)، ص ص. 244-252، 9ص.
الناشر
جامعة السلطان قابوس كلية الطب و العلوم الصحية
تاريخ النشر
2021-05-31
دولة النشر
سلطنة عمان
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objectives : this study was conducted to assess pregnancy outcomes in women with systemic lupus erythematosus (SLE) in Oman.
methods : a retrospective cohort study of 149 pregnancies in 98 women with SLE was conducted over 10 years to evaluate the impact of clinical and laboratory parameters in predicting adverse pregnancy outcomes.
results : mean maternal age was 30.6 ± 5 years ranging from 20–44 years, and the mean disease duration was 10 ± 5 years, ranging from 2–27 years.
the most common maternal manifestations were joint pain in 36 (24.2%), lupus nephritis (LN) in 18 (12.08%), preeclampsia in 11 (7.4%), eclampsia in three (2%) and lupus flare in one pregnancy.
the live birth rate was 139 (93.3%) with a mean gestational age of 36 ± 2 weeks ranging from 26–40 weeks.
in total, 55 (39.6%) were preterm deliveries, six (4%) pregnancies ended in miscarriage, and four (2.7%) resulted in intrauterine fetal death.
Intrauterine growth restriction was observed in 49 babies(35%).
A significant association was found between hypertension (HTN) and miscarriage (P = 0.024) and preterm birth (P = 0.019).
In addition, HTN was positively associated with preeclampsia (P = 0.004) and LN (P = 0.048).
antiphospholipid syndrome impacted preterm birth (P = 0.013) and postpartem haemorrhage (PPH) (P = 0.027) and was found to be a significant predictor for women developing deep vein thrombosis and pulmonary embolism(P <0.001 for both).
conclusion : despite potential complications, most pregnancies complicated by SLE in Oman result in good outcomes.
adverse pregnancy outcomes, however, may still occur in women with SLE.
In women with SLE, pregnancy planning, careful antenatal monitoring and efficient SLE treatment need to be undertaken for successful pregnancy outcomes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Riyami, Nihal& Salman, Bushra& al-Rashidi, Amani& al-Dughaishi, Tamima& al-Haddabi, Rahmah& Hasan, Batul Ali. 2021. Pregnancy outcomes in systemic lupus erythematosus women : a single tertiary centre experience. Sultan Qaboos University Medical Journal،Vol. 21, no. 2, pp.244-252.
https://search.emarefa.net/detail/BIM-1344810
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Riyami, Nihal…[et al.]. Pregnancy outcomes in systemic lupus erythematosus women : a single tertiary centre experience. Sultan Qaboos University Medical Journal Vol. 21, no. 2 (May. 2021), pp.244-252.
https://search.emarefa.net/detail/BIM-1344810
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Riyami, Nihal& Salman, Bushra& al-Rashidi, Amani& al-Dughaishi, Tamima& al-Haddabi, Rahmah& Hasan, Batul Ali. Pregnancy outcomes in systemic lupus erythematosus women : a single tertiary centre experience. Sultan Qaboos University Medical Journal. 2021. Vol. 21, no. 2, pp.244-252.
https://search.emarefa.net/detail/BIM-1344810
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 251-252
رقم السجل
BIM-1344810
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر