Potential ameliorative effects of corn silk on hepatic damage induced by carbon tetrachloride in experimental rats

المؤلف

Fahmi, Tasnim Subhi

المصدر

The Scientific Journal of Specific Education and Applied Sciences

العدد

المجلد 4، العدد 9 (31 ديسمبر/كانون الأول 2021)، ص ص. 200-223، 24ص.

الناشر

جامعة الفيوم كلية التربية النوعية

تاريخ النشر

2021-12-31

دولة النشر

مصر

عدد الصفحات

24

التخصصات الرئيسية

التغذية والحميات

الموضوعات

الملخص EN

This study was carried out to investigate the ameliorative effect of corn silk on hepatic damage in rats.

Thirty-five albino rats of Sprague-Dawley strain were randomly distributed after the adaptation period into two main groups (7 of each), the first main group was kept on the basal diet as negative control (-ve), The rest of the animals (n = 28) were subcutaneously injected with a single dose of CCl4 for the induction of necrosis.

After injection of CCL4, rats were divided into 4 subgroups.

The first subgroup of rats was as a positive control group (+ve).

The other subgroups were fed on the experimental diets containing different levels of corn silk 5% , 7.5% and 10% , respectively.

At the end of the experimental period (6 weeks) liver and kidney functions were determined.

Also, antioxidants enzymes in addition MDA were determined.

Histopathological examination for liver and kidneys were done.

The results indicated that liver enzymes including ALT, AST, ALP in addition albumin, total and direct bilirubin were decreased in groups 3, 4 and 5, respectively compared with the positive control group.

Urea nitrogen and creatinine were significantly improved in all tested groups compared with the positive control one.

Moreover, antioxidant enzymes (SOD and CAT) were significantly improved in all examined groups compared with the positive control group.

However, serum MDA decreased significantly in tested groups which were treated with 5% , 7.5% , and 10% corn silk when compared with the positive control group.

It could be concluded that corn silk had a potential effect against hepatic damage therefore this study recommends increasing dietary intake of corn silk could be beneficial for patients with hepatic damage.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Fahmi, Tasnim Subhi. 2021. Potential ameliorative effects of corn silk on hepatic damage induced by carbon tetrachloride in experimental rats. The Scientific Journal of Specific Education and Applied Sciences،Vol. 4, no. 9, pp.200-223.
https://search.emarefa.net/detail/BIM-1355088

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Fahmi, Tasnim Subhi. Potential ameliorative effects of corn silk on hepatic damage induced by carbon tetrachloride in experimental rats. The Scientific Journal of Specific Education and Applied Sciences Vol. 4, no. 9 (Dec. 2021), pp.200-223.
https://search.emarefa.net/detail/BIM-1355088

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Fahmi, Tasnim Subhi. Potential ameliorative effects of corn silk on hepatic damage induced by carbon tetrachloride in experimental rats. The Scientific Journal of Specific Education and Applied Sciences. 2021. Vol. 4, no. 9, pp.200-223.
https://search.emarefa.net/detail/BIM-1355088

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

-

رقم السجل

BIM-1355088