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Identification and quantification of secondary metabolites and the antimicrobial efficacy of leaves extracts of some medicinal plants
المؤلفون المشاركون
Nurudeen, Quadri Olaide
Falana, Mansurat Bolanle
المصدر
ZANCO Journal of Pure and Applied Sciences
العدد
المجلد 33، العدد 1 (28 فبراير/شباط 2021)، ص ص. 91-106، 16ص.
الناشر
جامعة صلاح الدين قسم النشر العلمي
تاريخ النشر
2021-02-28
دولة النشر
العراق
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
Azadirachta indica, Calotropis procera, Carica papaya, and Vernonia amygdalina are among the most frequently used plants with proven ethnomedicinal applications in Ilorin, Nigeria.
This study investigated the active constituents and antimicrobial efficacy of acetone and aqueous extracts of these plants against Candida albicans, Escherichia coli ATCC 259220, and Staphylococcus aureus ATCC 25923 by the disc diffusion technique.
High-Performance Liquid Chromatography (HPLC) fingerprint of the constituents of acetone extracts of C.
papaya, A.
indica, and V.
amygdalina was further investigated.
Highest percentage yield (10.20 %) was obtained for acetone extract of A.
indica while the lowest yield (10.20 %) was obtained for aqueous extract of C.
papaya.
Varying constituents viz.
coumarins, glycosides, protein, saponin, anthraquinone, flavonoid, tannin and terpenoid were detected.
Different levels of antimicrobial efficacy were exhibited by each of the plants while a synergistic effect was observed at 100 mg/mL concentration of acetone extract of the combination of all the plants.
An array of compounds was separated at different peak heights corresponding to concentration of the compounds.
Creptolepinone was detected in highest percentage (47.0 %) in acetone extracts of C.
papaya while phorbolester was detected in lowest percentage (1.2 %).
Myricetin was detected in highest percentage (39.6 %) in acetone extracts of A.
indica while alpha funebren was detected in lowest percentage (1.5 %).
Vernodalin was detected in highest peak height (48.8 %) in V.
amygdalina and andrographoside was detected in lowest peak height (0.6 %).
This study depicts that the plants may be promising pharmaceutical candidates that can be used in the development of new therapeutic agents.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nurudeen, Quadri Olaide& Falana, Mansurat Bolanle. 2021. Identification and quantification of secondary metabolites and the antimicrobial efficacy of leaves extracts of some medicinal plants. ZANCO Journal of Pure and Applied Sciences،Vol. 33, no. 1, pp.91-106.
https://search.emarefa.net/detail/BIM-1387887
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nurudeen, Quadri Olaide& Falana, Mansurat Bolanle. Identification and quantification of secondary metabolites and the antimicrobial efficacy of leaves extracts of some medicinal plants. ZANCO Journal of Pure and Applied Sciences Vol. 33, no. 1 (2021), pp.91-106.
https://search.emarefa.net/detail/BIM-1387887
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nurudeen, Quadri Olaide& Falana, Mansurat Bolanle. Identification and quantification of secondary metabolites and the antimicrobial efficacy of leaves extracts of some medicinal plants. ZANCO Journal of Pure and Applied Sciences. 2021. Vol. 33, no. 1, pp.91-106.
https://search.emarefa.net/detail/BIM-1387887
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 103-106
رقم السجل
BIM-1387887
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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