![](/images/graphics-bg.png)
Identification and quantification of secondary metabolites and the antimicrobial efficacy of leaves extracts of some medicinal plants
Joint Authors
Nurudeen, Quadri Olaide
Falana, Mansurat Bolanle
Source
ZANCO Journal of Pure and Applied Sciences
Issue
Vol. 33, Issue 1 (28 Feb. 2021), pp.91-106, 16 p.
Publisher
Salahaddin University-Erbil Department of Scientific Publications
Publication Date
2021-02-28
Country of Publication
Iraq
No. of Pages
16
Main Subjects
Abstract EN
Azadirachta indica, Calotropis procera, Carica papaya, and Vernonia amygdalina are among the most frequently used plants with proven ethnomedicinal applications in Ilorin, Nigeria.
This study investigated the active constituents and antimicrobial efficacy of acetone and aqueous extracts of these plants against Candida albicans, Escherichia coli ATCC 259220, and Staphylococcus aureus ATCC 25923 by the disc diffusion technique.
High-Performance Liquid Chromatography (HPLC) fingerprint of the constituents of acetone extracts of C.
papaya, A.
indica, and V.
amygdalina was further investigated.
Highest percentage yield (10.20 %) was obtained for acetone extract of A.
indica while the lowest yield (10.20 %) was obtained for aqueous extract of C.
papaya.
Varying constituents viz.
coumarins, glycosides, protein, saponin, anthraquinone, flavonoid, tannin and terpenoid were detected.
Different levels of antimicrobial efficacy were exhibited by each of the plants while a synergistic effect was observed at 100 mg/mL concentration of acetone extract of the combination of all the plants.
An array of compounds was separated at different peak heights corresponding to concentration of the compounds.
Creptolepinone was detected in highest percentage (47.0 %) in acetone extracts of C.
papaya while phorbolester was detected in lowest percentage (1.2 %).
Myricetin was detected in highest percentage (39.6 %) in acetone extracts of A.
indica while alpha funebren was detected in lowest percentage (1.5 %).
Vernodalin was detected in highest peak height (48.8 %) in V.
amygdalina and andrographoside was detected in lowest peak height (0.6 %).
This study depicts that the plants may be promising pharmaceutical candidates that can be used in the development of new therapeutic agents.
American Psychological Association (APA)
Nurudeen, Quadri Olaide& Falana, Mansurat Bolanle. 2021. Identification and quantification of secondary metabolites and the antimicrobial efficacy of leaves extracts of some medicinal plants. ZANCO Journal of Pure and Applied Sciences،Vol. 33, no. 1, pp.91-106.
https://search.emarefa.net/detail/BIM-1387887
Modern Language Association (MLA)
Nurudeen, Quadri Olaide& Falana, Mansurat Bolanle. Identification and quantification of secondary metabolites and the antimicrobial efficacy of leaves extracts of some medicinal plants. ZANCO Journal of Pure and Applied Sciences Vol. 33, no. 1 (2021), pp.91-106.
https://search.emarefa.net/detail/BIM-1387887
American Medical Association (AMA)
Nurudeen, Quadri Olaide& Falana, Mansurat Bolanle. Identification and quantification of secondary metabolites and the antimicrobial efficacy of leaves extracts of some medicinal plants. ZANCO Journal of Pure and Applied Sciences. 2021. Vol. 33, no. 1, pp.91-106.
https://search.emarefa.net/detail/BIM-1387887
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 103-106
Record ID
BIM-1387887