Protective role of pomegranate and sodium bicarbonate on acute renal failure induced by gentamicin in rabbits model

المؤلف

Qasim, Firas Khalid

المصدر

ZANCO Journal of Pure and Applied Sciences

الناشر

جامعة صلاح الدين قسم النشر العلمي

تاريخ النشر

2017-08-31

دولة النشر

العراق

عدد الصفحات

16

التخصصات الرئيسية

الأحياء

الملخص الإنجليزي

Acute renal failure ARF is common condition can be categorized as prerenal, intrinsic or postrenal causes in which the glomerular filtration rate decreases GFR over days to weeks .

The aim of this study was to test whether the administration of pomegranate and sodium bicarbonate minimize the adverse health effect of acute renal failure.

Methods : twenty female rabbits were assessed in to five groups ( n = 4 ) ,Group 1 : control group (C) .Group 2 : Gentamicin group ( G ): animals were injected with a single dose of Gentamicin ( 80 mg / Kg / bw ) intramuscular , daily for 10 days to induce renal failure.

Group 3 : sodium bicarbonate group ( G+S ),animals were treated as in group 2 plus they received sodium bicarbonate ( 1 ml / Kg / bw ) of 8.4% by gavage daily for 10 days .Group 4 : pomegranate group ( G+P ),animals were treated as in group 2 plus they received pomegranate 500 ( mg / Kg / bw ) by gavage.

Group 5 : combination group ( G+S+P ),animals were

نوع البيانات

أوراق مؤتمرات

رقم السجل

BIM-1388809

• APA
• MLA
• AMA