Protective role of pomegranate and sodium bicarbonate on acute renal failure induced by gentamicin in rabbits model

Author

Qasim, Firas Khalid

Source

ZANCO Journal of Pure and Applied Sciences

Publisher

Salahaddin University-Erbil Department of Scientific Publications

Publication Date

2017-08-31

Country of Publication

Iraq

No. of Pages

16

Main Subjects

Biology

English Abstract

Acute renal failure ARF is common condition can be categorized as prerenal, intrinsic or postrenal causes in which the glomerular filtration rate decreases GFR over days to weeks .

The aim of this study was to test whether the administration of pomegranate and sodium bicarbonate minimize the adverse health effect of acute renal failure.

Methods : twenty female rabbits were assessed in to five groups ( n = 4 ) ,Group 1 : control group (C) .Group 2 : Gentamicin group ( G ): animals were injected with a single dose of Gentamicin ( 80 mg / Kg / bw ) intramuscular , daily for 10 days to induce renal failure.

Group 3 : sodium bicarbonate group ( G+S ),animals were treated as in group 2 plus they received sodium bicarbonate ( 1 ml / Kg / bw ) of 8.4% by gavage daily for 10 days .Group 4 : pomegranate group ( G+P ),animals were treated as in group 2 plus they received pomegranate 500 ( mg / Kg / bw ) by gavage.

Group 5 : combination group ( G+S+P ),animals were

Data Type

Conference Papers

Record ID

BIM-1388809

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