Anti-obesity effect of some herbal mixtures (anise, fennel, mint, and black seed)‎ in a high-fat diet-induced obese rats

الملخص EN

Stoutness is a complex persistent illness where strange or overabundance of muscle versus fat (adiposity) debilitates well-being, expands the danger of unexpected long-haul issues, and diminishes life length.

The current research aimed to examine the counterweight impact of some home-grown blends (Anise, Fennel, Mint and Black Seed) on prompted fat rats.

Thirty adult male albino Sprague-Dawley rats were partitioned into two main groups.

As an ordinary benchmark group, the first group (6 rats) benefited from a basal diet (BD).

The second main group (24 rats) was benefited from a high-fat eating regimen that incited corpulence then, at that point, characterized into four equivalent sub gatherings as follows: group (2), as a positive control group, fed on BD and groups (3-5) fed on BD containing 2.5, 5.0 and 7.5% (w/w) the tried home-grown blends (anise, fennel, mint and black Seed) for 28 days, individually.

Results showed that obesity-induced disturbance in BWG, FI, FER and organs (liver, kidney and spleen) weight of obese rats.

Also, liver and kidney functions, serum lipid profile and serum glucose levels were affected.

Treatment of the obese rats with tested herbal mixtures (anise, fennel, mint, and black Seed) led to improvements in all of those parameters, and a dose-response behavior was recorded.

Finally, the histological examination data agreed with the biological and biochemical results obtained.

In conclusion, these discoveries give a premise to utilizing natural combinations (anise, fennel, mint and black seed) for the early treatment of obesity.