Stereotactic radiosurgery (SRS) experience on brain metastases : a 3-year retrospective study at King Abdulaziz University Hospital
المؤلفون المشاركون
Iskandarani, Umar
al-Wassiah, Rulina Kamal Hasan
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 28، العدد 9 (30 سبتمبر/أيلول 2021)، ص ص. 5042-5047، 6ص.
الناشر
تاريخ النشر
2021-09-30
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives: Stereotactic radiosurgery (SRS), a non-invasive surgical procedure had been utilized for treatment of patients with brain metastases.
This study aims to determine the survival, local control of brain metastases and treatment outcome to SRS-treated patients based on radiological imaging.
Methods: The MRI scans of SRS-treated patients with brain metastases (n = 24) from the Radiology Department of King Abdulaziz University from January 2016 to September 2019 were examined.
The data was analyzed using descriptive statistics and Chi-square test.
Results: Out of 24 patients, most had brain metastases (95.8%, n = 23) with mean interval development (after primary site) of 21.88 ± 25.2 months.
Radiological imaging revealed tumor characteristics of smallest (n = 11) and biggest lesions (n = 24) of patients to be 0.98 ± 0.7 and 2.23 ± 0.9, respectively and number of lesion to be 4-5 lesions (n = 3), 3 lesions (n = 6), 2 lesions (n = 4) and 1 lesion (n = 11).
After SRS treatment, findings showed 17.6% (n = 3) no recurrence among the patients.
Those with recurrences have decrease in lesion enhancement (11.8%, n = 2), decrease in size (29.4%, n = 5) and decrease in both enhancement and size (29.4%).
Overall survival obtained was 16.7% (n = 2) at 313.83 ± 376.0 days (n = 23) survival period.
Chi-square test showed that radiological findings were significantly associated with tumor recurrence (p = 0.010), having SRS-treated patients with recurrences (n = 12) to experience significant decrease (p = 0.010) in tumor enhancement, size, and both enhancement and size.
Conclusion: A significant decrease in tumor size and enhancement was observed in SRS-treated patients, suggesting SRS treatment to have associated benefit with prolonged survival duration.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Wassiah, Rulina Kamal Hasan& Iskandarani, Umar. 2021. Stereotactic radiosurgery (SRS) experience on brain metastases : a 3-year retrospective study at King Abdulaziz University Hospital. Saudi Journal of Biological Sciences،Vol. 28, no. 9, pp.5042-5047.
https://search.emarefa.net/detail/BIM-1410148
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Wassiah, Rulina Kamal Hasan& Iskandarani, Umar. Stereotactic radiosurgery (SRS) experience on brain metastases : a 3-year retrospective study at King Abdulaziz University Hospital. Saudi Journal of Biological Sciences Vol. 28, no. 9 (2021), pp.5042-5047.
https://search.emarefa.net/detail/BIM-1410148
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Wassiah, Rulina Kamal Hasan& Iskandarani, Umar. Stereotactic radiosurgery (SRS) experience on brain metastases : a 3-year retrospective study at King Abdulaziz University Hospital. Saudi Journal of Biological Sciences. 2021. Vol. 28, no. 9, pp.5042-5047.
https://search.emarefa.net/detail/BIM-1410148
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5046-5047
رقم السجل
BIM-1410148
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر