Determination of synergistic effects of antibiotics and Zno NPs against isolated E. Coli and A. Baumannii bacterial strains from clinical samples
المؤلفون المشاركون
al-Sharif, Fadwa Ubayd Sulayman
al-Barraq, Ahmad Muhammad
al-Qublan, Dina K.
Mateen, Aishah
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 28، العدد 9 (30 سبتمبر/أيلول 2021)، ص ص. 5332-5337، 6ص.
الناشر
تاريخ النشر
2021-09-30
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The mortality rates has been increased globally due to multidrug resistant (MDR) E.coli and A.baumanii bacterial strains and also there is an emerging resistance of the Enterobacteriaceae family of bacteria to Carbapenem antibiotics (CRE) in Saudi Arabia.
The main aim of our research study is to isolate E.coli and A.
baumannii bacterial species from various collected clinical samples and to evaluate the MIC and FICI of Colistin, Ciprofloxacin, Meropenem and ZnO NPs and in combination of Colistin, Ciprofloxacin, Meropenem with ZnO NPs.
The clinical isolated strains of A.
baumannii (MRO-17-13) and A.
baumannii (MRO-17-25) was found to be sensitive towards colistin with 0.5 μg/mL concentration, whereas, all the isolated A.
baumannii strains showed similar MIC value 2 mg/mL when tested with ZnO NPs, the MIC value for the ZnO NPs was found to be similar for all the E.coli strains 0.25 mg/mL.
The effects of all Ciprofloxacin concentrations used in the study were bacteriostatic against E.
coli (01UR19006568-01) strain but 1 mg/mL concentration of ZnO NPs alone is showed bactericidal activity, ZnO NPs effect was found to be concentration dependent, as highest concentration of ZnO NPs showed strongest antibacterial effect.
In conclusion, more investigation is required to evaluate the acceptable concentration of Zno NPs and antibiotics selected to avoid toxicity and must be tested against more clinically isolated gram-negative bacterial strains.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Sharif, Fadwa Ubayd Sulayman& al-Barraq, Ahmad Muhammad& al-Qublan, Dina K.& Mateen, Aishah. 2021. Determination of synergistic effects of antibiotics and Zno NPs against isolated E. Coli and A. Baumannii bacterial strains from clinical samples. Saudi Journal of Biological Sciences،Vol. 28, no. 9, pp.5332-5337.
https://search.emarefa.net/detail/BIM-1411368
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Barraq, Ahmad Muhammad…[et al.]. Determination of synergistic effects of antibiotics and Zno NPs against isolated E. Coli and A. Baumannii bacterial strains from clinical samples. Saudi Journal of Biological Sciences Vol. 28, no. 9 (2021), pp.5332-5337.
https://search.emarefa.net/detail/BIM-1411368
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Sharif, Fadwa Ubayd Sulayman& al-Barraq, Ahmad Muhammad& al-Qublan, Dina K.& Mateen, Aishah. Determination of synergistic effects of antibiotics and Zno NPs against isolated E. Coli and A. Baumannii bacterial strains from clinical samples. Saudi Journal of Biological Sciences. 2021. Vol. 28, no. 9, pp.5332-5337.
https://search.emarefa.net/detail/BIM-1411368
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5337
رقم السجل
BIM-1411368
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر