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In vitro examination of anti-parasitic, anti-Alzheimer, insecticidal and cytotoxic potential of Ajuga bracteosa Wallich leaves extracts
المؤلفون المشاركون
Khan, Muhammad Naim Allah
Umran, Muhammad
Faisal, Shah
Jan, Hasanayn
Shah, Sajjad Ali
Shah, Sumairah
Akbar, Muhammad Taj
Jan, Fahim
Sayyid, Sulayman
Radwan, Muhammad
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 28، العدد 5 (31 مايو/أيار 2021)، ص ص. 3031-3036، 6ص.
الناشر
تاريخ النشر
2021-05-31
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
علم الاجتماع و الأنثروبولوجيا و الخدمة الاجتماعية
الملخص EN
This research study is mainly focused to evaluate the anti-parasitic, insecticidal, cytotoxic and anti- alzheimer potential of various leaf extracts of Ajuga bracteosa Wallich ex Bentham.
04 different extracts were prepared using solvent of different polarity to determine the best candidate for potent bioactivity i.e.
n-hexane (NH), Ethyl acetate (EA), Ethanol (EL) and Chloroform (CH).
Concentrations of each extracts were made specified for all activities.
All extracts were exploited for broad range of biomedical applica- tions including leishmaniasis, in vitro anti-Alzheimer, insecticidal and cytotoxic studies.
Our results showed that A.
bracteosa n-hexane extract was highly active against Leishmania Tropica with significant inhibition of 58 ± 1.61 for promastigote and 63 ± 2.29 for amastigote at 1000 lg/mL.
Furthermore, promising anti-alzheimer activity acetylcholinesterase (AChE) 46 ± 0.83 and butrylcholineterase (BChE) 49 ± 1.17 was noted for n-hexane.
The insecticidal potential of these extracts were test against five different insects (Rhyzopertha dominica, Trogoderma granarium, Tribolium castaneum, Sitophilus oryze, and Callosobruchus analis).
The higest mortality rate of insecticidal activity was recorded by n-hexane fol- lowed by Ethyl acetate whereas ethanol extract was found to be less effective against all the test species.
Significant cytotoxic potential of each plant sample against Artemia salina thus aware us for further detailed research to find out novel drugs.
Based on our results we believe that Ajuga bracteosa could be used to develop as a potential botanical insecticide against different insect and pests, such as aphids as well as an excellent source for the compound isolation as anti-tumor agent.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Umran, Muhammad& Jan, Hasanayn& Faisal, Shah& Shah, Sajjad Ali& Shah, Sumairah& Khan, Muhammad Naim Allah…[et al.]. 2021. In vitro examination of anti-parasitic, anti-Alzheimer, insecticidal and cytotoxic potential of Ajuga bracteosa Wallich leaves extracts. Saudi Journal of Biological Sciences،Vol. 28, no. 5, pp.3031-3036.
https://search.emarefa.net/detail/BIM-1419241
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Umran, Muhammad…[et al.]. In vitro examination of anti-parasitic, anti-Alzheimer, insecticidal and cytotoxic potential of Ajuga bracteosa Wallich leaves extracts. Saudi Journal of Biological Sciences Vol. 28, no. 5 (2021), pp.3031-3036.
https://search.emarefa.net/detail/BIM-1419241
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Umran, Muhammad& Jan, Hasanayn& Faisal, Shah& Shah, Sajjad Ali& Shah, Sumairah& Khan, Muhammad Naim Allah…[et al.]. In vitro examination of anti-parasitic, anti-Alzheimer, insecticidal and cytotoxic potential of Ajuga bracteosa Wallich leaves extracts. Saudi Journal of Biological Sciences. 2021. Vol. 28, no. 5, pp.3031-3036.
https://search.emarefa.net/detail/BIM-1419241
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 3035-3036
رقم السجل
BIM-1419241
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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