Prevalence of congenital cytomegalovirus infection among hospitalized neonates in Tehran, Iran
المؤلفون المشاركون
Ridai, Farhad
Jumah, Husam al-Din Imam
Farahmand, Majid
Haghighi, Fayizah
Izadpanahi, Maryam
Nurbakhsh, Samileh
Farhadi, Muhammad
Hasanabad, M. Haghighi
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 22، العدد 10 (31 أكتوبر/تشرين الأول 2020)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2020-10-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background: Cytomegalovirus (CMV) can vertically transmit from infected mothers to fetuses and causes congenital infection in newborns.
Unfortunately, there have been limited data available on the prevalence of congenital CMV (cCMV) infection among Iranian neonates at higher risk of infection.
Objectives: The current study aimed to assess the prevalence of cCMV infection among hospitalized neonates in Tehran, Iran, and investigate the diagnostic values of CMV polymerase chain reaction (PCR) on Guthrie cards in comparison to those reported for urine specimens.
Methods: This cross-sectional study was carried out on the hospitalized neonates with 3 weeks of age.
The urine specimens and Guthrie cards were taken from each eligible newborn.
Total nucleic acid was extracted from the samples and tested by PCR for the presence of CMV deoxyribonucleic acid.
The cCMV infection was confirmed in the newborns, and the infected neonates underwent further evaluation.
Results: Out of 224 newborns, CMV infection was identified in 11 neonates (4.9%).
There were no factors in association with cCMV infection.
The sensitivity and specificity of dried blood spot (DBS) samples for the identification of newborns with cCMV infection were 90% and 99%, respectively.
Conclusion: A significant number of hospitalized neonates in the present study were infected with cCMV infection.
The results of the current study revealed that Guthrie cards had adequate sensitivity for the identification of CMV infection in the hospitalized newborns.
Since symptomatic newborns with cCMV infection have a higher chance for the development of early- or late-onset sequelae of infection, it is recommended to diagnose and treat this group of newborns.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Farhadi, Muhammad& Ridai, Farhad& Jumah, Husam al-Din Imam& Farahmand, Majid& Haghighi, Fayizah& Izadpanahi, Maryam…[et al.]. 2020. Prevalence of congenital cytomegalovirus infection among hospitalized neonates in Tehran, Iran. Iranian Red Crescent Medical Journal،Vol. 22, no. 10, pp.1-6.
https://search.emarefa.net/detail/BIM-1430684
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Farhadi, Muhammad…[et al.]. Prevalence of congenital cytomegalovirus infection among hospitalized neonates in Tehran, Iran. Iranian Red Crescent Medical Journal Vol. 22, no. 10 (Oct. 2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1430684
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Farhadi, Muhammad& Ridai, Farhad& Jumah, Husam al-Din Imam& Farahmand, Majid& Haghighi, Fayizah& Izadpanahi, Maryam…[et al.]. Prevalence of congenital cytomegalovirus infection among hospitalized neonates in Tehran, Iran. Iranian Red Crescent Medical Journal. 2020. Vol. 22, no. 10, pp.1-6.
https://search.emarefa.net/detail/BIM-1430684
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-1430684
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر