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Monitoring of the CD4+ T cell subsets among Sudanese HIV sero-positive individuals
المصدر
العدد
المجلد 2022، العدد 13 (s) (28 فبراير/شباط 2022)، ص ص. 119-132، 14ص.
الناشر
مركز بحوث و دراسات دول حوض البحر الأحمر
تاريخ النشر
2022-02-28
دولة النشر
السودان
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Purpose: HIVAIDS is developing major health problem in Sudan.
This study investigate the CD4+ level among Sudanese HIV sero-positive subjects with and without AIDS symptoms in comparison to the HIV sero-negative control to establish base line data about CD4+ count in HIV infection in Sudan.
Methods: Eighty-six individuals were selected for this study, their age ranged between (13 –53) years, (60) subjects were males and 26 were females.
The HIV seropositive were 60, of whom 54 were AIDS patients.
The presence of HIV specific antibodies was detected and confirmed by ELISA and immunoblotting techniques according to WHO criteria.
CD4 and CD8 were counting by Dynabeads T4- T8 Quantitative method.
Results: CD4+ and CD8+ levels were counted together Differential of TWBCs.
Significant lower counts of CD4+ were detected among AIDS/HIV patients compared with AIDS/HIV sero-negative individuals.
Increased of CD4+ counts were observed among treated AIDS/HIV patients.
No significant differences detected in either CD8+ count or the total WBCs in HIV seropositive and se-ronegative subjects.
Conclusion: The counting of CD4+ T lymphocytes is important in the staging of AIDS/HIV disease for various purposes such as deciding when to initiate prophylactic or therapeutic intervention, and in monitoring the response following antiretroviral treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Majdhub, Majdhub A.& Naurin, Ayman Mudawi& Mukhtar, Muhammad& al-Khudayr, Isam Muhammad. 2022. Monitoring of the CD4+ T cell subsets among Sudanese HIV sero-positive individuals. Al-ghulzum Scientific Journal،Vol. 2022, no. 13 (s), pp.119-132.
https://search.emarefa.net/detail/BIM-1436129
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Majdhub, Majdhub A.…[et al.]. Monitoring of the CD4+ T cell subsets among Sudanese HIV sero-positive individuals. Al-ghulzum Scientific Journal No. 13 (Special issue) (Feb. 2022), pp.119-132.
https://search.emarefa.net/detail/BIM-1436129
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Majdhub, Majdhub A.& Naurin, Ayman Mudawi& Mukhtar, Muhammad& al-Khudayr, Isam Muhammad. Monitoring of the CD4+ T cell subsets among Sudanese HIV sero-positive individuals. Al-ghulzum Scientific Journal. 2022. Vol. 2022, no. 13 (s), pp.119-132.
https://search.emarefa.net/detail/BIM-1436129
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 131-132
رقم السجل
BIM-1436129
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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