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Efficacy of intra articular botulinum toxin injection in sickle cell patients’ joints
المؤلفون المشاركون
Turani, Badriyah
Ahmad, Uways
al-Mashhur, Mutasim
al-Mansuri, Nada
Ashri, Shakir
المصدر
Journal of the Bahrain Medical Society
العدد
المجلد 32، العدد 3 (30 سبتمبر/أيلول 2020)، ص ص. 1-8، 8ص.
الناشر
تاريخ النشر
2020-09-30
دولة النشر
البحرين
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background: Sickle cell disease patients have a tendency for vaso-occlusive attacks involving their bones.
Osteonecrosis results in infarction of the articular surfaces and heads of long bones, leading to chronic joint pain, significant interference in functioning and quality of life.
Intraarticular Botox injection is safe andreduces chronic pain while patients’ mobility.
Objective: The study aimed to evaluate the symptomatic change and its duration after intra-articular Botox injection, in sickle cell disease patients with chronic pain.
Methods: Sickle cell disease patients with chronic joint pain observed at Salmaniya medical complex were included.
Patients were injected with Botox intraarticularly and followed up for a year.Symptomatic parameters were assessed at every follow- up, raw data collected was entered into Microsoft Excel spreadsheet were the numerical variables analyzed and graphs were created.
Results: Forty-eight sickle cell disease patients were included.Postthe intraarticular injection at 3 months, the level of pain according to, Numerical rating scale (NRS) reduced by 44.6 % (p-value <0.005) and 27.8%( p-value < 0.001) at 6 months and 9.54% ( p-value <0.01) at 1 year, and significant improvement of other parameters.
Conclusion: Intraarticular BoNT/ A injection provides an alternative treatment in sickle disease patients with good results in reduction of pain, improved physical function, mood, and sleep pattern lasting at least 6 months.
Although a small scale study, the results suggest that BoNT/ A is an effective and safe treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Mashhur, Mutasim& Turani, Badriyah& al-Mansuri, Nada& Ashri, Shakir& Ahmad, Uways. 2020. Efficacy of intra articular botulinum toxin injection in sickle cell patients’ joints. Journal of the Bahrain Medical Society،Vol. 32, no. 3, pp.1-8.
https://search.emarefa.net/detail/BIM-1437573
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Mashhur, Mutasim…[et al.]. Efficacy of intra articular botulinum toxin injection in sickle cell patients’ joints. Journal of the Bahrain Medical Society Vol. 32, no. 3 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1437573
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Mashhur, Mutasim& Turani, Badriyah& al-Mansuri, Nada& Ashri, Shakir& Ahmad, Uways. Efficacy of intra articular botulinum toxin injection in sickle cell patients’ joints. Journal of the Bahrain Medical Society. 2020. Vol. 32, no. 3, pp.1-8.
https://search.emarefa.net/detail/BIM-1437573
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 7-8
رقم السجل
BIM-1437573
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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