Proteinuria in adult Saudi patients with sickle cell disease is not associated with identifiable risk factors
المؤلف
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 21، العدد 5 (31 أكتوبر/تشرين الأول 2010)، ص ص. 903-908، 6ص.
الناشر
تاريخ النشر
2010-10-31
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Renal involvement in patients with sickle cell disease (SCD) is associated with significant morbidity and mortality.
Proteinuria is common in patients with SCD and is a risk factor for future development of renal failure.
We sought to identify risk factors, if any, associated with proteinuria in adult Saudi patients with SCD.
We studied 67 patients with SCD followed-up at the King Khalid University Hospital, Riyadh, Saudi Arabia.
All patients underwent 24-hour urine collection to measure creatinine clearance and to quantify proteinuria.
In addition, blood was examined for evaluation of hematological and biochemical parameters.
Clinical information was gathered from review of the patients' charts.
A urine protein level of more than 0.150 grams/24 hours was considered abnormal.
Urine protein was correlated with various clinical and laboratory parameters.
Thirtyone males and 36 females were evaluated.
The mean age of the cohort was 23.8 (± 7.2) years.
Twenty-seven patients (40.3%) had proteinuria of more than 0.150 grams/24 hours.
The study group had a mean hemoglobin level of 8.5 (± 2.8) g/dL and mean fetal hemoglobin (HbF) level of 14.4% (± 7.3%).
Majority of the patients (61) had hemoglobin SS genotype and six patients had S-?0 thalassemia.
None of the parameters evaluated correlated with proteinuria although there was a borderline association with older age and higher systolic blood pressure (P = 0.073 and 0.061 respectively).
Hydroxyurea use for more than a year was not beneficial.
In conclusion, our study suggests that proteinuria in adult Saudi patients is not associated with any clear identifiable risk factors.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Alim, Amir. 2010. Proteinuria in adult Saudi patients with sickle cell disease is not associated with identifiable risk factors. Saudi Journal of Kidney Diseases and Transplantation،Vol. 21, no. 5, pp.903-908.
https://search.emarefa.net/detail/BIM-216680
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Alim, Amir. Proteinuria in adult Saudi patients with sickle cell disease is not associated with identifiable risk factors. Saudi Journal of Kidney Diseases and Transplantation Vol. 21, no. 5 (Oct. 2010), pp.903-908.
https://search.emarefa.net/detail/BIM-216680
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Alim, Amir. Proteinuria in adult Saudi patients with sickle cell disease is not associated with identifiable risk factors. Saudi Journal of Kidney Diseases and Transplantation. 2010. Vol. 21, no. 5, pp.903-908.
https://search.emarefa.net/detail/BIM-216680
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 907-908
رقم السجل
BIM-216680
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر