Pattern of glomerular diseases in Sudanese children : a clinico-pathological study
المؤلفون المشاركون
Abd al-Rahim, Muhammad B.
al-Tijani, M. A. Ali
Muhammad, Rim M.
Hassan, Inas G.
Makki, Salwa O.
Yusuf, B. M.
Abd Allah, Usamah Ali Muhammad
Watson, Alan R.
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 21، العدد 4 (30 أغسطس/آب 2010)، ص ص. 778-783، 6ص.
الناشر
تاريخ النشر
2010-08-30
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Glomerular diseases are a common cause of chronic kidney disease (CKD) in many countries.
The pattern of glomerular diseases has been reported in adult Sudanese patients but there has been no previous study on Sudanese children.
The aim of this study is to describe the pattern of glomerular diseases in Sudanese children from a clinico-pathological perspective.
We retrospectively reviewed the clinical records of 321 children seen with nephritis/nephrosis at the Pediatric Nephrology Unit, Soba University Hospital and Dr.
Salma Dialysis and Kidney Transplantation Centre, Khartoum, Sudan during the period from 2002 to 2007.
Biopsies were studied with light microscopy and immunohistochemistry with electron microscopy performed abroad in selected patients (predominantly Alport's).
The mean age of the 321 study children was 8.71 years (range 2 months-16 yrs) of whom, 188 were males (60.2%).
The most common presentation was with the nephrotic syndrome, seen in 202 patients (62.9%).
The most common glomerular disease encountered was minimal change disease, seen in 96 children (29.9%), followed by post-infectious GN in 78 (24.3%) and focal and segmental glomerulosclerosis, seen in 44 patients (13.7%).
Membranoproliferative GN (MPGN) was seen in 43 patients (13.4%) while mesangioproliferative GN was seen in 24 (7.5%).
Systemic lupus erythematosus (SLE) was the most common secondary glomerular disease accounting for 16 patients (4.9%).
HBsAg was positive in 10 patients and the most common associated lesion was MPGN (60%).
Histopathology enabled us to change the therapy in 55.3% of the patients.
Our study suggests that the pattern of GN in our cohort of patients is comparable with reports from other parts of the world with a high prevalence of post-infectious GN.
Renal biopsies have an important part in planning therapy and management.
Also, the importance of establishing a Sudanese renal registry including pediatric patients is stressed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abd al-Rahim, Muhammad B.& al-Tijani, M. A. Ali& Muhammad, Rim M.& Abd Allah, Usamah Ali Muhammad& Makki, Salwa O.& Yusuf, B. M.…[et al.]. 2010. Pattern of glomerular diseases in Sudanese children : a clinico-pathological study. Saudi Journal of Kidney Diseases and Transplantation،Vol. 21, no. 4, pp.778-783.
https://search.emarefa.net/detail/BIM-219680
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abd al-Rahim, Muhammad B.…[et al.]. Pattern of glomerular diseases in Sudanese children : a clinico-pathological study. Saudi Journal of Kidney Diseases and Transplantation Vol. 21, no. 4 (Sep. 2010), pp.778-783.
https://search.emarefa.net/detail/BIM-219680
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abd al-Rahim, Muhammad B.& al-Tijani, M. A. Ali& Muhammad, Rim M.& Abd Allah, Usamah Ali Muhammad& Makki, Salwa O.& Yusuf, B. M.…[et al.]. Pattern of glomerular diseases in Sudanese children : a clinico-pathological study. Saudi Journal of Kidney Diseases and Transplantation. 2010. Vol. 21, no. 4, pp.778-783.
https://search.emarefa.net/detail/BIM-219680
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 782-783.
رقم السجل
BIM-219680
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر