Transient synovitis versus septic arthritis of the hip : the value of esr&wbc count

الملخص EN

which were divided into 4 groups ,the control group (7rats) received distilled water, the other three treatment groups each group (14) rats were divided into two subgroups T1 & T2 according to the following oral daily dosing regimen (aspirin subgroup 2and 4mg / kg, captopril, 6 and 12 mg / kg and asprin + captopril (2 + 6mg / kg and 4 + 12 mg / kg)respectively.

The following biochemical and hematological results were recorded during the experiment: Aspartate Transaminase : significant increase (p<0.05) were observed in the serum of rats treated subgroups T1 & T2of captopril and captopril + asprin after 3 month while asprin showed a significant increase in serum AST level started from 1.5 months for T2 group.

Alanine Transeaminase : Catopril ,asprin and captopril + asprin treated rats showed significant increase(P<0.05) in serum ALT level in both T1 & T2subgroups at the period of 1.5 &3 months treatment positively proportional with the dose and treatment period.

Alkaline Phosphatase : Captopril, asprin and captopril + asprin treated rats showed highest levels with significant increase (P<0.05)in serum APlevels in both T1 & T2subgroup at the period of 1.5 & 3 months treatment positively proportional with the dose and treatment period.