Synthesis of some new 4-(3h)‎-quinazoline analogs as potential antioxidant agents

الملخص EN

A new series of 6-iodo-2-propyl-4 (3H)-quinazolinone and its fused heterocyclic were prepared and screened for their antioxidant activity.

It was found that compounds 4, 5, 7, 9, 10, 20 and 24 inhibit aldehyde oxidase exclusively by more than 98%.

This type of inhibition was found to be competitive with Ki value ranging from 50-400 µM with respect to aldehyde oxidase.