Synthesis of some new 4-(3h)-quinazoline analogs as potential antioxidant agents
Joint Authors
al-Azab, Adil S.
al-Umar, M. A.
al-Ubayd, H. A.
S.G. Abd al-Hamid
Source
Journal of Saudi Chemical Society
Issue
Vol. 10, Issue 1 (30 May. 2006), pp.113-127, 15 p.
Publisher
Publication Date
2006-05-30
Country of Publication
Saudi Arabia
No. of Pages
15
Main Subjects
Topics
Abstract AR
في هذا البحث تم تحضير بعض المماثلات الجديدة من الكينازولين -4- أون كمضادات للأكسدة و تم إثبات البناء الكيماوي للمركبات الجديدة بواسطة التحليل الدقيق للعناصر و الأشعة تحت الحمراء و الرنين النووي المغناطيسي و كذلك مطياف الكتلة و قد ثبت لبعضها فاعلية كبيرة في إيقاف فاعلية أنزيم ألدهيد أو كسيديز بنسبة أكبر من 98 %.
Abstract EN
A new series of 6-iodo-2-propyl-4 (3H)-quinazolinone and its fused heterocyclic were prepared and screened for their antioxidant activity.
It was found that compounds 4, 5, 7, 9, 10, 20 and 24 inhibit aldehyde oxidase exclusively by more than 98%.
This type of inhibition was found to be competitive with Ki value ranging from 50-400 µM with respect to aldehyde oxidase.
American Psychological Association (APA)
al-Umar, M. A.& al-Azab, Adil S.& al-Ubayd, H. A.& S.G. Abd al-Hamid. 2006. Synthesis of some new 4-(3h)-quinazoline analogs as potential antioxidant agents. Journal of Saudi Chemical Society،Vol. 10, no. 1, pp.113-127.
https://search.emarefa.net/detail/BIM-24383
Modern Language Association (MLA)
al-Umar, M. A.…[et al.]. Synthesis of some new 4-(3h)-quinazoline analogs as potential antioxidant agents. Journal of Saudi Chemical Society (May. 2006), pp.113-127.
https://search.emarefa.net/detail/BIM-24383
American Medical Association (AMA)
al-Umar, M. A.& al-Azab, Adil S.& al-Ubayd, H. A.& S.G. Abd al-Hamid. Synthesis of some new 4-(3h)-quinazoline analogs as potential antioxidant agents. Journal of Saudi Chemical Society. 2006. Vol. 10, no. 1, pp.113-127.
https://search.emarefa.net/detail/BIM-24383
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 127
Record ID
BIM-24383
