![](/images/graphics-bg.png)
Expansion of human marrow derived mesenchymal stem cells and their transdifferentiation potential
المؤلفون المشاركون
Ayatollahi, M.
Salmani, M. Kabir
Soleimani, M.
Sanati, Muhammad Husayn
Gardaneh, M.
Tabei, S. Z.
Gerami zadah, Bita
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 12، العدد 4 (31 يوليو/تموز 2010)، ص ص. 446-452، 7ص.
الناشر
تاريخ النشر
2010-07-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : the ability of mesenchyme stem cells (MSCs) to differentiate into other cell types makes these cells an attractive therapeutic tool for cell transplantation.
In order to provide a source of human MSCs for autologous cell-based therapy, we have expanded MSCs from the bone marrow and analyzed the biological identities and trans differentiation potential.
Methods : The bone marrow of healthy donors was aspirated from the iliac crest.
The adjacent cells expanded rapidly and maintained with periodic passages until a relatively homogeneous population was established.
The identification of these cells was carried out by differentiation potential into the osteocytes and adipocytes.
Trans differentiation of human MSCs into hepatocyte-like cells was undertaken in response to a specific culture condition.
Results : the differentiation of MSCs into osteoblast is determined by deposition of a mineralized extracellular matrix.
Adipocytes are identified by their morphology and staining.
Hepatic cells were demonstrated in vitro functions characteristic of liver cells.
Conclusion : we have defined conditions under which human MSCs can be isolated and expanded from human bone marrow.
These cells can be amplified about 108-fold in 6 weeks, and are capable of trans differentiation into the cells of another developmental lineage.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ayatollahi, M.& Salmani, M. Kabir& Soleimani, M.& Gerami zadah, Bita& Sanati, Muhammad Husayn& Gardaneh, M.…[et al.]. 2010. Expansion of human marrow derived mesenchymal stem cells and their transdifferentiation potential. Iranian Red Crescent Medical Journal،Vol. 12, no. 4, pp.446-452.
https://search.emarefa.net/detail/BIM-252571
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ayatollahi, M.…[et al.]. Expansion of human marrow derived mesenchymal stem cells and their transdifferentiation potential. Iranian Red Crescent Medical Journal Vol. 12, no. 4 (Jul. 2010), pp.446-452.
https://search.emarefa.net/detail/BIM-252571
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ayatollahi, M.& Salmani, M. Kabir& Soleimani, M.& Gerami zadah, Bita& Sanati, Muhammad Husayn& Gardaneh, M.…[et al.]. Expansion of human marrow derived mesenchymal stem cells and their transdifferentiation potential. Iranian Red Crescent Medical Journal. 2010. Vol. 12, no. 4, pp.446-452.
https://search.emarefa.net/detail/BIM-252571
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 451-452
رقم السجل
BIM-252571
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)